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Interneuron diversity
Sodium channels as anesthetic targets
Volatile anesthetic effects on intracellular Ca2+ dynamics influence synaptic vesicle exocytosis
Volatile anesthetics directly bind Nav
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Role of genetic polymorphisms in anesthetic-induced effects on synaptic function and structure.
Spine plasticity in anesthetic action
Voltage gated sodium channels (Nav) and hyperexcitability in early Alzheimer Disease.
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Found 84 results
Author
Title
Type
Year
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Hemmings, Hugh C
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2014
Huang V
,
Hemmings HC
,
Crews D
. 2014.
Sociosexual investigation in sexually experienced, hormonally manipulated male leopard geckos: relation with phosphorylated DARPP-32 in dopaminergic pathways.
.
J Exp Zool A Ecol Genet Physiol. 321(10):595-602.
Herold KF
,
R Sanford L
,
Lee W
,
Schultz MF
,
Ingólfsson HI
,
Andersen OS
,
Hemmings HC
. 2014.
Volatile anesthetics inhibit sodium channels without altering bulk lipid bilayer properties.
.
J Gen Physiol. 144(6):545-60.
2015
Baumgart JP
,
Zhou Z-Y
,
Hara M
,
Cook DC
,
Hoppa MB
,
Ryan TA
,
Hemmings HC
. 2015.
Isoflurane inhibits synaptic vesicle exocytosis through reduced Ca2+ influx, not Ca2+-exocytosis coupling.
.
Proc Natl Acad Sci U S A. 112(38):11959-64.
2016
Riegelhaupt PM
,
Hemmings HC
,
Goldstein PA
. 2016.
Relevance of Clinical Relevance.
.
Anesthesiology. 125(4):821-2.
Hara M
,
Zhou Z-Y
,
Hemmings HC
. 2016.
α2-Adrenergic Receptor and Isoflurane Modulation of Presynaptic Ca2+ Influx and Exocytosis in Hippocampal Neurons.
.
Anesthesiology. 125(3):535-46.
2017
Herold KF
,
R Sanford L
,
Lee W
,
Andersen OS
,
Hemmings HC
. 2017.
Clinical concentrations of chemically diverse general anesthetics minimally affect lipid bilayer properties.
.
Proc Natl Acad Sci U S A. 114(12):3109-3114.
Herold KF
,
Andersen OS
,
Hemmings HC
. 2017.
Divergent effects of anesthetics on lipid bilayer properties and sodium channel function.
.
Eur Biophys J. 46(7):617-626.
Sand RM
,
Gingrich KJ
,
Macharadze T
,
Herold KF
,
Hemmings HC
. 2017.
Isoflurane modulates activation and inactivation gating of the prokaryotic Na channel NaChBac.
.
J Gen Physiol. 149(6):623-638.
Johnson KW
,
Herold KF
,
Milner TA
,
Hemmings HC
,
Platholi J
. 2017.
Sodium channel subtypes are differentially localized to pre- and post-synaptic sites in rat hippocampus.
.
J Comp Neurol. 525(16):3563-3578.
2019
Hemmings HC
. 2019.
Change management: the British Journal of Anaesthesia in 2018.
.
Br J Anaesth. 122(1):1-3.
Zhou C
,
Johnson KW
,
Herold KF
,
Hemmings HC
. 2019.
Differential Inhibition of Neuronal Sodium Channel Subtypes by the General Anesthetic Isoflurane.
.
J Pharmacol Exp Ther. 369(2):200-211.
Hemmings HC
,
Lambert DG
. 2019.
The good, the bad, and the ugly: the many faces of opioids.
.
Br J Anaesth. 122(6):705-707.
Torturo CL
,
Zhou Z-Y
,
Ryan TA
,
Hemmings HC
. 2019.
Isoflurane Inhibits Dopaminergic Synaptic Vesicle Exocytosis Coupled to Ca2.1 and Ca2.2 in Rat Midbrain Neurons.
.
eNeuro. 6(1)
Zhao W
,
Zhang M
,
Liu J
,
Liang P
,
Wang R
,
Hemmings HC
,
Zhou C
. 2019.
Isoflurane Modulates Hippocampal Cornu Ammonis Pyramidal Neuron Excitability by Inhibition of Both Transient and Persistent Sodium Currents in Mice.
.
Anesthesiology. 131(1):94-104.
Koyanagi Y
,
Torturo CL
,
Cook DC
,
Zhou Z
,
Hemmings HC
. 2019.
Role of specific presynaptic calcium channel subtypes in isoflurane inhibition of synaptic vesicle exocytosis in rat hippocampal neurones.
.
Br J Anaesth. 123(2):219-227.
Hemmings HC
,
Riegelhaupt PM
,
Kelz MB
,
Solt K
,
Eckenhoff RG
,
Orser BA
,
Goldstein PA
. 2019.
Towards a Comprehensive Understanding of Anesthetic Mechanisms of Action: A Decade of Discovery.
.
Trends Pharmacol Sci. 40(7):464-481.
2020
Leslie K
,
Hemmings HC
. 2020.
Excellence in editorials: fulfilling their critical role in the medical literature.
.
Br J Anaesth. 125(5):639-641.
Hemmings HC
,
Shafer SL
. 2020.
Further retractions of articles by Joachim Boldt.
.
Br J Anaesth. 125(3):409-411.
Asai T
,
O'Sullivan EP
,
Hemmings HC
. 2020.
A special issue on respiration and the airway: critical topics at a challenging time.
.
Br J Anaesth. 125(1):1-4.
Wong CA
,
S Moonesinghe R
,
Boer C
,
Hemmings HC
,
Hunter JM
. 2020.
Women in anaesthesia, a special issue of the British Journal of Anaesthesia.
.
Br J Anaesth. 124(3):e40-e43.
2021
Zhao W
,
Zhao S
,
Zhu T
,
Ou M
,
Zhang D
,
Sun H
,
Liu J
,
Chen X
,
Hemmings HC
,
Zhou C
. 2021.
Isoflurane Suppresses Hippocampal High-frequency Ripples by Differentially Modulating Pyramidal Neurons and Interneurons in Mice.
.
Anesthesiology. 135(1):122-135.
Platholi J
,
Hemmings HC
. 2021.
Modulation of dendritic spines by protein phosphatase-1.
.
Adv Pharmacol. 90:117-144.
Pearse RM
,
Ackland GL
,
Asai T
,
Hemmings HC
. 2021.
Preprints in perioperative medicine: immediacy for the greater good.
.
Br J Anaesth. 126(5):915-918.
Speigel IA
,
Hemmings HC
. 2021.
Relevance of Cortical and Hippocampal Interneuron Functional Diversity to General Anesthetic Mechanisms: A Narrative Review.
.
Front Synaptic Neurosci. 13:812905.
Speigel IA
,
Hemmings HC
. 2021.
Selective inhibition of gamma aminobutyric acid release from mouse hippocampal interneurone subtypes by the volatile anaesthetic isoflurane.
.
Br J Anaesth. 127(4):587-599.
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