Publications

Westphalen RI, Hemmings HC.  2003.  Selective depression by general anesthetics of glutamate versus GABA release from isolated cortical nerve terminals.. J Pharmacol Exp Ther. 304(3):1188-96.

Hazlett EA, Buchsbaum MS, Kemether E, Bloom R, Platholi J, Brickman AM, Shihabuddin L, Tang C, Byne W.  2004.  Abnormal glucose metabolism in the mediodorsal nucleus of the thalamus in schizophrenia.. Am J Psychiatry. 161(2):305-14.

Bálint E, Kitka T, Zachar G, Adám A, Hemmings HC, Csillag A.  2004.  Abundance and location of DARPP-32 in striato-tegmental circuits of domestic chicks.. J Chem Neuroanat. 28(1-2):27-36.

Perouansky M, Hemmings HC, Pearce RA.  2004.  Anesthetic effects on glutamatergic neurotransmission: lessons learned from a large synapse.. Anesthesiology. 100(3):470-2.

Ouyang W, Wang G, Hemmings HC.  2004.  Distinct rat neurohypophysial nerve terminal populations identified by size, electrophysiological properties and neuropeptide content.. Brain Res. 1024(1-2):203-11.

Hemmings HC.  2004.  Neuroprotection by Na+ channel blockade.. J Neurosurg Anesthesiol. 16(1):100-1.

Morrow PW, Tung HYLim, Hemmings HC.  2004.  Rapamycin causes activation of protein phosphatase-2A1 and nuclear translocation of PCNA in CD4+ T cells.. Biochem Biophys Res Commun. 323(2):645-51.

Hazlett EA, Buchsbaum MS, Hsieh P, M Haznedar M, Platholi J, LiCalzi EM, Cartwright C, Hollander E.  2004.  Regional glucose metabolism within cortical Brodmann areas in healthy individuals and autistic patients.. Neuropsychobiology. 49(3):115-25.

OuYang W, Hemmings HC.  2005.  Depression by isoflurane of the action potential and underlying voltage-gated ion currents in isolated rat neurohypophysial nerve terminals.. J Pharmacol Exp Ther. 312(2):801-8.

Hemmings HC, Akabas MH, Goldstein PA, Trudell JR, Orser BA, Harrison NL.  2005.  Emerging molecular mechanisms of general anesthetic action.. Trends Pharmacol Sci. 26(10):503-10.

Hemmings HC, Yan W, Westphalen RI, Ryan TA.  2005.  The general anesthetic isoflurane depresses synaptic vesicle exocytosis.. Mol Pharmacol. 67(5):1591-9.

Futter M, Uematsu K, Bullock SA, Kim Y, Hemmings HC, Nishi A, Greengard P, Nairn AC.  2005.  Phosphorylation of spinophilin by ERK and cyclin-dependent PK 5 (Cdk5).. Proc Natl Acad Sci U S A. 102(9):3489-94.

Fu D, Vissavajjhala P, Hemmings HC.  2005.  Volatile anaesthetic effects on phospholipid binding to synaptotagmin 1, a presynaptic Ca2+ sensor.. Br J Anaesth. 95(2):216-21.

Bruening S, Oh E, Hetzenauer A, Escobar-Alvarez S, Westphalen RI, Hemmings HC, Singewald N, Shippenberg T, Toth M.  2006.  The anxiety-like phenotype of 5-HT receptor null mice is associated with genetic background-specific perturbations in the prefrontal cortex GABA-glutamate system.. J Neurochem. 99(3):892-9.

Hotte M, Thuault S, Lachaise F, Dineley KT, Hemmings HC, Nairn AC, Jay TM.  2006.  D1 receptor modulation of memory retrieval performance is associated with changes in pCREB and pDARPP-32 in rat prefrontal cortex.. Behav Brain Res. 171(1):127-33.

Hemmings HC, Antognini JF.  2006.  Do general anesthetics add up? Anesthesiology. 104(6):1120-2.

Yun S-W, Platholi J, Flaherty MSol, Fu W, Kottmann AH, Toth M.  2006.  Fmrp is required for the establishment of the startle response during the critical period of auditory development.. Brain Res. 1110(1):159-65.

Buchsbaum MS, Hollander E, Pallanti S, Rossi NBaldini, Platholi J, Newmark R, Bloom R, Sood E.  2006.  Positron emission tomography imaging of risperidone augmentation in serotonin reuptake inhibitor-refractory patients.. Neuropsychobiology. 53(3):157-68.

Westphalen RI, Hemmings HC.  2006.  Volatile anesthetic effects on glutamate versus GABA release from isolated rat cortical nerve terminals: basal release.. J Pharmacol Exp Ther. 316(1):208-15.

Westphalen RI, Hemmings HC.  2006.  Volatile anesthetic effects on glutamate versus GABA release from isolated rat cortical nerve terminals: 4-aminopyridine-evoked release.. J Pharmacol Exp Ther. 316(1):216-23.

S Bullock A, Platholi J, Gjyrezi A, Heerdt PM, Tung HYLim, Hemmings HC.  2007.  Differential regulation of protein phosphatase-1(I) by neurabin.. Biochem Biophys Res Commun. 358(1):140-4.

Snyder GL, Galdi S, Hendrick JP, Hemmings HC.  2007.  General anesthetics selectively modulate glutamatergic and dopaminergic signaling via site-specific phosphorylation in vivo.. Neuropharmacology. 53(5):619-30.

OuYang W, Jih T-Y, Zhang T-T, Correa AM, Hemmings HC.  2007.  Isoflurane inhibits NaChBac, a prokaryotic voltage-gated sodium channel.. J Pharmacol Exp Ther. 322(3):1076-83.

OuYang W, Hemmings HC.  2007.  Isoform-selective effects of isoflurane on voltage-gated Na+ channels.. Anesthesiology. 107(1):91-8.

Hemmings HC.  2007.  Noble meets nouveau: a shared anesthetic binding site for xenon and isoflurane on a glutamate receptor.. Anesthesiology. 107(5):694-6.