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Interneuron diversity
Sodium channels as anesthetic targets
Volatile anesthetic effects on intracellular Ca2+ dynamics influence synaptic vesicle exocytosis
Volatile anesthetics directly bind Nav
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Role of genetic polymorphisms in anesthetic-induced effects on synaptic function and structure.
Spine plasticity in anesthetic action
Voltage gated sodium channels (Nav) and hyperexcitability in early Alzheimer Disease.
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Found 32 results
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2021
Pearse RM, Ackland GL, Asai T, Hemmings HC
. 2021.
Preprints in perioperative medicine: immediacy for the greater good.
.
Br J Anaesth. 126(5):915-918.
Pearse RM, Ackland GL, Asai T, Hemmings HC
. 2021.
Preprints in perioperative medicine: immediacy for the greater good.
.
Br J Anaesth. 126(5):915-918.
2020
Asai T, O'Sullivan EP, Hemmings HC
. 2020.
A special issue on respiration and the airway: critical topics at a challenging time.
.
Br J Anaesth. 125(1):1-4.
2017
Herold KF, R Sanford L, Lee W, Andersen OS, Hemmings HC
. 2017.
Clinical concentrations of chemically diverse general anesthetics minimally affect lipid bilayer properties.
.
Proc Natl Acad Sci U S A. 114(12):3109-3114.
Herold KF, Andersen OS, Hemmings HC
. 2017.
Divergent effects of anesthetics on lipid bilayer properties and sodium channel function.
.
Eur Biophys J. 46(7):617-626.
2014
Ingólfsson HI, Thakur P, Herold KF, E Hobart A, Ramsey NB, Periole X, de Jong DH, Zwama M, Yilmaz D, Hall K et al.
. 2014.
Phytochemicals perturb membranes and promiscuously alter protein function.
.
ACS Chem Biol. 9(8):1788-98.
Herold KF, R Sanford L, Lee W, Schultz MF, Ingólfsson HI, Andersen OS, Hemmings HC
. 2014.
Volatile anesthetics inhibit sodium channels without altering bulk lipid bilayer properties.
.
J Gen Physiol. 144(6):545-60.
2013
Jevtovic-Todorovic V, Absalom AR, Blomgren K, Brambrink A, Crosby G, Culley DJ, Fiskum G, Giffard RG, Herold KF, Loepke AW et al.
. 2013.
Anaesthetic neurotoxicity and neuroplasticity: an expert group report and statement based on the BJA Salzburg Seminar.
.
Br J Anaesth. 111(2):143-51.
Tibbs GR, Rowley TJ, R Sanford L, Herold KF, Proekt A, Hemmings HC, Andersen OS, Goldstein PA, Flood PD
. 2013.
HCN1 channels as targets for anesthetic and nonanesthetic propofol analogs in the amelioration of mechanical and thermal hyperalgesia in a mouse model of neuropathic pain.
.
J Pharmacol Exp Ther. 345(3):363-73.
2011
Rusinova R, Herold KF, R Sanford L, Greathouse DV, Hemmings HC, Andersen OS
. 2011.
Thiazolidinedione insulin sensitizers alter lipid bilayer properties and voltage-dependent sodium channel function: implications for drug discovery.
.
J Gen Physiol. 138(2):249-70.
2007
Westphalen RI, Krivitski M, Amarosa A, Guy N, Hemmings HC
. 2007.
Reduced inhibition of cortical glutamate and GABA release by halothane in mice lacking the K+ channel, TREK-1.
.
Br J Pharmacol. 152(6):939-45.
2006
Hemmings HC, Antognini JF
. 2006.
Do general anesthetics add up?
Anesthesiology. 104(6):1120-2.
2005
Hemmings HC, Akabas MH, Goldstein PA, Trudell JR, Orser BA, Harrison NL
. 2005.
Emerging molecular mechanisms of general anesthetic action.
.
Trends Pharmacol Sci. 26(10):503-10.
2004
Bálint E, Kitka T, Zachar G, Adám A, Hemmings HC, Csillag A
. 2004.
Abundance and location of DARPP-32 in striato-tegmental circuits of domestic chicks.
.
J Chem Neuroanat. 28(1-2):27-36.
2002
Albert KA, Hemmings HC, Adamo AIB, Potkin SG, Akbarian S, Sandman CA, Cotman CW, Bunney WE, Greengard P
. 2002.
Evidence for decreased DARPP-32 in the prefrontal cortex of patients with schizophrenia.
.
Arch Gen Psychiatry. 59(8):705-12.
Albert KA, Hemmings HC, Adamo AIB, Potkin SG, Akbarian S, Sandman CA, Cotman CW, Bunney WE, Greengard P
. 2002.
Evidence for decreased DARPP-32 in the prefrontal cortex of patients with schizophrenia.
.
Arch Gen Psychiatry. 59(8):705-12.
Albert KA, Hemmings HC, Adamo AIB, Potkin SG, Akbarian S, Sandman CA, Cotman CW, Bunney WE, Greengard P
. 2002.
Evidence for decreased DARPP-32 in the prefrontal cortex of patients with schizophrenia.
.
Arch Gen Psychiatry. 59(8):705-12.
2001
Absil P, Foidart A, Hemmings HC, Steinbusch HW, Ball GF, Balthazart J
. 2001.
Distribution of DARPP-32 immunoreactive structures in the quail brain: anatomical relationship with dopamine and aromatase.
.
J Chem Neuroanat. 21(1):23-39.
1999
McAvoy T, Allen PB, Obaishi H, Nakanishi H, Takai Y, Greengard P, Nairn AC, Hemmings HC
. 1999.
Regulation of neurabin I interaction with protein phosphatase 1 by phosphorylation.
.
Biochemistry. 38(39):12943-9.
1997
Hemmings HC, Adamo AI
. 1997.
Effect of halothane on conventional protein kinase C translocation and down-regulation in rat cerebrocortical synaptosomes.
.
Br J Anaesth. 78(2):189-96.
1996
Hemmings HC, Adamo AI
. 1996.
Activation of endogenous protein kinase C by halothane in synaptosomes.
.
Anesthesiology. 84(3):652-62.
Lien CA, Hemmings HC, Belmont MR, Abalos A, Hollmann C, Kelly RE
. 1996.
A comparison: the efficacy of sevoflurane-nitrous oxide or propofol-nitrous oxide for the induction and maintenance of general anesthesia.
.
J Clin Anesth. 8(8):639-43.
Chang S, Hemmings HC, Aderem A
. 1996.
Stimulus-dependent phosphorylation of MacMARCKS, a protein kinase C substrate, in nerve termini and PC12 cells.
.
J Biol Chem. 271(2):1174-8.
1995
Hemmings HC, Adamo AI, Hoffman MM
. 1995.
Biochemical characterization of the stimulatory effects of halothane and propofol on purified brain protein kinase C.
.
Anesth Analg. 81(6):1216-22.
1994
Hemmings HC, Adamo AI
. 1994.
Effects of halothane and propofol on purified brain protein kinase C activation.
.
Anesthesiology. 81(1):147-55.
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