Publications

Hemmings HC, Riegelhaupt PM, Kelz MB, Solt K, Eckenhoff RG, Orser BA, Goldstein PA.  2019.  Towards a Comprehensive Understanding of Anesthetic Mechanisms of Action: A Decade of Discovery.. Trends Pharmacol Sci. 40(7):464-481.

Sand RM, Gingrich KJ, Macharadze T, Herold KF, Hemmings HC.  2017.  Isoflurane modulates activation and inactivation gating of the prokaryotic Na channel NaChBac.. J Gen Physiol. 149(6):623-638.

Riegelhaupt PM, Hemmings HC, Goldstein PA.  2016.  Relevance of Clinical Relevance.. Anesthesiology. 125(4):821-2.

Purtell K, Gingrich KJ, Ouyang W, Herold KF, Hemmings HC.  2015.  Activity-dependent depression of neuronal sodium channels by the general anaesthetic isoflurane.. Br J Anaesth. 115(1):112-21.

Buggy DJ, Borgeat A, Cata J, Doherty DG, Doornebal CW, Forget P, Gottumukkala V, Gottschalk A, Gupta A, Gupta K et al..  2015.  Consensus statement from the BJA Workshop on Cancer and Anaesthesia.. Br J Anaesth. 114(1):2-3.

Buggy DJ, Borgeat A, Cata J, Doherty DG, Doornebal CW, Forget P, Gottumukkala V, Gottschalk A, Gupta A, Gupta K et al..  2015.  Consensus statement from the BJA Workshop on Cancer and Anaesthesia.. Br J Anaesth. 114(1):2-3.

Buggy DJ, Borgeat A, Cata J, Doherty DG, Doornebal CW, Forget P, Gottumukkala V, Gottschalk A, Gupta A, Gupta K et al..  2015.  Consensus statement from the BJA Workshop on Cancer and Anaesthesia.. Br J Anaesth. 114(1):2-3.

Buggy DJ, Borgeat A, Cata J, Doherty DG, Doornebal CW, Forget P, Gottumukkala V, Gottschalk A, Gupta A, Gupta K et al..  2015.  Consensus statement from the BJA Workshop on Cancer and Anaesthesia.. Br J Anaesth. 114(1):2-3.

Giambrone GP, Hemmings HC, Sturm M, Fleischut PM.  2015.  Information technology innovation: the power and perils of big data.. Br J Anaesth. 115(3):339-42.

Jevtovic-Todorovic V, Absalom AR, Blomgren K, Brambrink A, Crosby G, Culley DJ, Fiskum G, Giffard RG, Herold KF, Loepke AW et al..  2013.  Anaesthetic neurotoxicity and neuroplasticity: an expert group report and statement based on the BJA Salzburg Seminar.. Br J Anaesth. 111(2):143-51.

Tibbs GR, Rowley TJ, R Sanford L, Herold KF, Proekt A, Hemmings HC, Andersen OS, Goldstein PA, Flood PD.  2013.  HCN1 channels as targets for anesthetic and nonanesthetic propofol analogs in the amelioration of mechanical and thermal hyperalgesia in a mouse model of neuropathic pain.. J Pharmacol Exp Ther. 345(3):363-73.

Walaas SIvar, Hemmings HCaroll, Greengard P, Nairn AClark.  2011.  Beyond the dopamine receptor: regulation and roles of serine/threonine protein phosphatases.. Front Neuroanat. 5:50.

Rusinova R, Herold KF, R Sanford L, Greathouse DV, Hemmings HC, Andersen OS.  2011.  Thiazolidinedione insulin sensitizers alter lipid bilayer properties and voltage-dependent sodium channel function: implications for drug discovery.. J Gen Physiol. 138(2):249-70.

Bendor J, Lizardi-Ortiz JE, Westphalen RI, Brandstetter M, Hemmings HC, Sulzer D, Flajolet M, Greengard P.  2010.  AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release.. EMBO J. 29(16):2813-26.

Zhang Y, Guzinski M, Eger EI, Laster MJ, Sharma M, Harris RA, Hemmings HC.  2010.  Bidirectional modulation of isoflurane potency by intrathecal tetrodotoxin and veratridine in rats.. Br J Pharmacol. 159(4):872-8.

Glausier JR, Maddox M, Hemmings HC, Nairn AC, Greengard P, Muly EC.  2010.  Localization of dopamine- and cAMP-regulated phosphoprotein-32 and inhibitor-1 in area 9 of Macaca mulatta prefrontal cortex.. Neuroscience. 167(2):428-38.

Glausier JR, Maddox M, Hemmings HC, Nairn AC, Greengard P, Muly EC.  2010.  Localization of dopamine- and cAMP-regulated phosphoprotein-32 and inhibitor-1 in area 9 of Macaca mulatta prefrontal cortex.. Neuroscience. 167(2):428-38.

Hemmings HC, Greengard P.  2010.  Positively active: how local anesthetics work.. Anesthesiology. 113(1):250-2.

Westphalen RI, Gomez RS, Hemmings HC.  2009.  Nicotinic receptor-evoked hippocampal norepinephrine release is highly sensitive to inhibition by isoflurane.. Br J Anaesth. 102(3):355-60.

S Bullock A, Platholi J, Gjyrezi A, Heerdt PM, Tung HYLim, Hemmings HC.  2007.  Differential regulation of protein phosphatase-1(I) by neurabin.. Biochem Biophys Res Commun. 358(1):140-4.

Snyder GL, Galdi S, Hendrick JP, Hemmings HC.  2007.  General anesthetics selectively modulate glutamatergic and dopaminergic signaling via site-specific phosphorylation in vivo.. Neuropharmacology. 53(5):619-30.

Westphalen RI, Krivitski M, Amarosa A, Guy N, Hemmings HC.  2007.  Reduced inhibition of cortical glutamate and GABA release by halothane in mice lacking the K+ channel, TREK-1.. Br J Pharmacol. 152(6):939-45.

Nguyen C, Nishi A, Kansy JW, Fernandez J, Hayashi K, Gillardon F, Hemmings HC, Nairn AC, Bibb JA.  2007.  Regulation of protein phosphatase inhibitor-1 by cyclin-dependent kinase 5.. J Biol Chem. 282(22):16511-20.

Hemmings HC, Akabas MH, Goldstein PA, Trudell JR, Orser BA, Harrison NL.  2005.  Emerging molecular mechanisms of general anesthetic action.. Trends Pharmacol Sci. 26(10):503-10.

Futter M, Uematsu K, Bullock SA, Kim Y, Hemmings HC, Nishi A, Greengard P, Nairn AC.  2005.  Phosphorylation of spinophilin by ERK and cyclin-dependent PK 5 (Cdk5).. Proc Natl Acad Sci U S A. 102(9):3489-94.