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Interneuron diversity
Sodium channels as anesthetic targets
Volatile anesthetic effects on intracellular Ca2+ dynamics influence synaptic vesicle exocytosis
Volatile anesthetics directly bind Nav
Dr. Platholi's Research Projects
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Role of genetic polymorphisms in anesthetic-induced effects on synaptic function and structure.
Spine plasticity in anesthetic action
Voltage gated sodium channels (Nav) and hyperexcitability in early Alzheimer Disease.
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Found 87 results
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2011
Rusinova R, Herold KF, R Sanford L, Greathouse DV, Hemmings HC, Andersen OS
. 2011.
Thiazolidinedione insulin sensitizers alter lipid bilayer properties and voltage-dependent sodium channel function: implications for drug discovery.
.
J Gen Physiol. 138(2):249-70.
2013
Jevtovic-Todorovic V, Absalom AR, Blomgren K, Brambrink A, Crosby G, Culley DJ, Fiskum G, Giffard RG, Herold KF, Loepke AW et al.
. 2013.
Anaesthetic neurotoxicity and neuroplasticity: an expert group report and statement based on the BJA Salzburg Seminar.
.
Br J Anaesth. 111(2):143-51.
Tibbs GR, Rowley TJ, R Sanford L, Herold KF, Proekt A, Hemmings HC, Andersen OS, Goldstein PA, Flood PD
. 2013.
HCN1 channels as targets for anesthetic and nonanesthetic propofol analogs in the amelioration of mechanical and thermal hyperalgesia in a mouse model of neuropathic pain.
.
J Pharmacol Exp Ther. 345(3):363-73.
2015
Purtell K, Gingrich KJ, Ouyang W, Herold KF, Hemmings HC
. 2015.
Activity-dependent depression of neuronal sodium channels by the general anaesthetic isoflurane.
.
Br J Anaesth. 115(1):112-21.
Buggy DJ, Borgeat A, Cata J, Doherty DG, Doornebal CW, Forget P, Gottumukkala V, Gottschalk A, Gupta A, Gupta K et al.
. 2015.
Consensus statement from the BJA Workshop on Cancer and Anaesthesia.
.
Br J Anaesth. 114(1):2-3.
Buggy DJ, Borgeat A, Cata J, Doherty DG, Doornebal CW, Forget P, Gottumukkala V, Gottschalk A, Gupta A, Gupta K et al.
. 2015.
Consensus statement from the BJA Workshop on Cancer and Anaesthesia.
.
Br J Anaesth. 114(1):2-3.
Buggy DJ, Borgeat A, Cata J, Doherty DG, Doornebal CW, Forget P, Gottumukkala V, Gottschalk A, Gupta A, Gupta K et al.
. 2015.
Consensus statement from the BJA Workshop on Cancer and Anaesthesia.
.
Br J Anaesth. 114(1):2-3.
Buggy DJ, Borgeat A, Cata J, Doherty DG, Doornebal CW, Forget P, Gottumukkala V, Gottschalk A, Gupta A, Gupta K et al.
. 2015.
Consensus statement from the BJA Workshop on Cancer and Anaesthesia.
.
Br J Anaesth. 114(1):2-3.
Giambrone GP, Hemmings HC, Sturm M, Fleischut PM
. 2015.
Information technology innovation: the power and perils of big data.
.
Br J Anaesth. 115(3):339-42.
2016
Riegelhaupt PM, Hemmings HC, Goldstein PA
. 2016.
Relevance of Clinical Relevance.
.
Anesthesiology. 125(4):821-2.
2017
Sand RM, Gingrich KJ, Macharadze T, Herold KF, Hemmings HC
. 2017.
Isoflurane modulates activation and inactivation gating of the prokaryotic Na channel NaChBac.
.
J Gen Physiol. 149(6):623-638.
2019
Hemmings HC, Riegelhaupt PM, Kelz MB, Solt K, Eckenhoff RG, Orser BA, Goldstein PA
. 2019.
Towards a Comprehensive Understanding of Anesthetic Mechanisms of Action: A Decade of Discovery.
.
Trends Pharmacol Sci. 40(7):464-481.
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