Publications

Williams KR, Hemmings HC, LoPresti MB, Konigsberg WH, Greengard P.  1986.  DARPP-32, a dopamine- and cyclic AMP-regulated neuronal phosphoprotein. Primary structure and homology with protein phosphatase inhibitor-1.. J Biol Chem. 261(4):1890-903.

Stone RA, Laties AM, Hemmings HC, Ouimet CC, Greengard P.  1986.  DARPP-32 in the ciliary epithelium of the eye: a neurotransmitter-regulated phosphoprotein of brain localizes to secretory cells.. J Histochem Cytochem. 34(11):1465-8.

Williams KR, Hemmings HC, LoPresti MB, Greengard P.  1989.  ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions. I. Amino acid sequence of ARPP-21B from bovine caudate nucleus.. J Neurosci. 9(10):3631-7.

Hemmings HC, Girault JA, Williams KR, LoPresti MB, Greengard P.  1989.  ARPP-21, a cyclic AMP-regulated phosphoprotein (Mr = 21,000) enriched in dopamine-innervated brain regions. Amino acid sequence of the site phosphorylated by cyclic AMP in intact cells and kinetic studies of its phosphorylation in vitro.. J Biol Chem. 264(13):7726-33.

Lien CA, Hemmings HC, Belmont MR, Abalos A, Hollmann C, Kelly RE.  1996.  A comparison: the efficacy of sevoflurane-nitrous oxide or propofol-nitrous oxide for the induction and maintenance of general anesthesia.. J Clin Anesth. 8(8):639-43.

Lingamaneni R, Hemmings HC.  1999.  Effects of anticonvulsants on veratridine- and KCl-evoked glutamate release from rat cortical synaptosomes.. Neurosci Lett. 276(2):127-30.

Lingameneni R, Vysotskaya TN, Duch DS, Hemmings HC.  2000.  Inhibition of voltage-dependent sodium channels by Ro 31-8220, a 'specific' protein kinase C inhibitor.. FEBS Lett. 473(2):265-8.

Lingamaneni R, Krasowski MD, Jenkins A, Truong T, Giunta AL, Blackbeer J, MacIver MB, Harrison NL, Hemmings HC.  2001.  Anesthetic properties of 4-iodopropofol: implications for mechanisms of anesthesia.. Anesthesiology. 94(6):1050-7.

Lingamaneni R, Birch ML, Hemmings HC.  2001.  Widespread inhibition of sodium channel-dependent glutamate release from isolated nerve terminals by isoflurane and propofol.. Anesthesiology. 95(6):1460-6.

Shahani SK, Lingamaneni R, Hemmings HC.  2002.  General anesthetic actions on norepinephrine, dopamine, and gamma-aminobutyric acid transporters in stably transfected cells.. Anesth Analg. 95(4):893-9,tableofcontents.

Lingamaneni R, Hemmings HC.  2003.  Differential interaction of anaesthetics and antiepileptic drugs with neuronal Na+ channels, Ca2+ channels, and GABA(A) receptors.. Br J Anaesth. 90(2):199-211.

Hazlett EA, Buchsbaum MS, Hsieh P, M Haznedar M, Platholi J, LiCalzi EM, Cartwright C, Hollander E.  2004.  Regional glucose metabolism within cortical Brodmann areas in healthy individuals and autistic patients.. Neuropsychobiology. 49(3):115-25.

Hotte M, Thuault S, Lachaise F, Dineley KT, Hemmings HC, Nairn AC, Jay TM.  2006.  D1 receptor modulation of memory retrieval performance is associated with changes in pCREB and pDARPP-32 in rat prefrontal cortex.. Behav Brain Res. 171(1):127-33.

Zhang Y, Sharma M, Eger EI, Laster MJ, Hemmings HC, R Harris A.  2008.  Intrathecal veratridine administration increases minimum alveolar concentration in rats.. Anesth Analg. 107(3):875-8.

Bendor J, Lizardi-Ortiz JE, Westphalen RI, Brandstetter M, Hemmings HC, Sulzer D, Flajolet M, Greengard P.  2010.  AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release.. EMBO J. 29(16):2813-26.

Zhang Y, Guzinski M, Eger EI, Laster MJ, Sharma M, Harris RA, Hemmings HC.  2010.  Bidirectional modulation of isoflurane potency by intrathecal tetrodotoxin and veratridine in rats.. Br J Pharmacol. 159(4):872-8.

Jevtovic-Todorovic V, Absalom AR, Blomgren K, Brambrink A, Crosby G, Culley DJ, Fiskum G, Giffard RG, Herold KF, Loepke AW et al..  2013.  Anaesthetic neurotoxicity and neuroplasticity: an expert group report and statement based on the BJA Salzburg Seminar.. Br J Anaesth. 111(2):143-51.

Herold KF, R Sanford L, Lee W, Schultz MF, Ingólfsson HI, Andersen OS, Hemmings HC.  2014.  Volatile anesthetics inhibit sodium channels without altering bulk lipid bilayer properties.. J Gen Physiol. 144(6):545-60.

Herold KF, R Sanford L, Lee W, Andersen OS, Hemmings HC.  2017.  Clinical concentrations of chemically diverse general anesthetics minimally affect lipid bilayer properties.. Proc Natl Acad Sci U S A. 114(12):3109-3114.

Hemmings HC, Lambert DG.  2019.  The good, the bad, and the ugly: the many faces of opioids.. Br J Anaesth. 122(6):705-707.

Zhao W, Zhang M, Liu J, Liang P, Wang R, Hemmings HC, Zhou C.  2019.  Isoflurane Modulates Hippocampal Cornu Ammonis Pyramidal Neuron Excitability by Inhibition of Both Transient and Persistent Sodium Currents in Mice.. Anesthesiology. 131(1):94-104.

Zhao W, Zhang M, Liu J, Liang P, Wang R, Hemmings HC, Zhou C.  2019.  Isoflurane Modulates Hippocampal Cornu Ammonis Pyramidal Neuron Excitability by Inhibition of Both Transient and Persistent Sodium Currents in Mice.. Anesthesiology. 131(1):94-104.

Leslie K, Hemmings HC.  2020.  Excellence in editorials: fulfilling their critical role in the medical literature.. Br J Anaesth. 125(5):639-641.

Zhao W, Zhao S, Zhu T, Ou M, Zhang D, Sun H, Liu J, Chen X, Hemmings HC, Zhou C.  2021.  Isoflurane Suppresses Hippocampal High-frequency Ripples by Differentially Modulating Pyramidal Neurons and Interneurons in Mice.. Anesthesiology. 135(1):122-135.

Williams RA, Johnson KW, Lee FS, Hemmings HC, Platholi J.  2022.  A Common Human Brain-Derived Neurotrophic Factor Polymorphism Leads to Prolonged Depression of Excitatory Synaptic Transmission by Isoflurane in Hippocampal Cultures.. Front Mol Neurosci. 15:927149.