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Interneuron diversity
Sodium channels as anesthetic targets
Volatile anesthetic effects on intracellular Ca2+ dynamics influence synaptic vesicle exocytosis
Volatile anesthetics directly bind Nav
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Role of genetic polymorphisms in anesthetic-induced effects on synaptic function and structure.
Spine plasticity in anesthetic action
Voltage gated sodium channels (Nav) and hyperexcitability in early Alzheimer Disease.
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Found 37 results
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2023
Osman V, Speigel I, Patel K, Hemmings HC
. 2023.
Isoflurane Alters Presynaptic Endoplasmic Reticulum Calcium Dynamics in Wild-Type and Malignant Hyperthermia-Susceptible Rodent Hippocampal Neurons.
.
eNeuro. 10(8)
Kaur G, Pryor KO, Milewski AR, Weinberg R, Hemmings HC
. 2023.
Torture mechanisms and chronic somatic pain in US refugees.
.
Br J Anaesth. 131(2):e41-e43.
2022
Williams RA, Johnson KW, Lee FS, Hemmings HC, Platholi J
. 2022.
A Common Human Brain-Derived Neurotrophic Factor Polymorphism Leads to Prolonged Depression of Excitatory Synaptic Transmission by Isoflurane in Hippocampal Cultures.
.
Front Mol Neurosci. 15:927149.
Speigel IA, Patel K, Hemmings HC
. 2022.
Distinct effects of volatile and intravenous anaesthetics on presynaptic calcium dynamics in mouse hippocampal GABAergic neurones.
.
Br J Anaesth. 128(6):1019-1028.
Platholi J, Hemmings HC
. 2022.
Effects of General Anesthetics on Synaptic Transmission and Plasticity.
.
Curr Neuropharmacol. 20(1):27-54.
2021
Platholi J, Hemmings HC
. 2021.
Modulation of dendritic spines by protein phosphatase-1.
.
Adv Pharmacol. 90:117-144.
Pearse RM, Ackland GL, Asai T, Hemmings HC
. 2021.
Preprints in perioperative medicine: immediacy for the greater good.
.
Br J Anaesth. 126(5):915-918.
2020
Kaur G, Weinberg R, Milewski ARobert, Huynh S, Mauer E, Hemmings HCarroll, Pryor KOwen
. 2020.
Chronic pain diagnosis in refugee torture survivors: A prospective, blinded diagnostic accuracy study.
.
PLoS Med. 17(6):e1003108.
2018
Perouansky M, Hemmings HC
. 2018.
Bioblasts, anaesthesia, and power failure: rein in the excitement.
.
Br J Anaesth. 120(5):891-895.
2017
Johnson KW, Herold KF, Milner TA, Hemmings HC, Platholi J
. 2017.
Sodium channel subtypes are differentially localized to pre- and post-synaptic sites in rat hippocampus.
.
J Comp Neurol. 525(16):3563-3578.
2015
Purtell K, Gingrich KJ, Ouyang W, Herold KF, Hemmings HC
. 2015.
Activity-dependent depression of neuronal sodium channels by the general anaesthetic isoflurane.
.
Br J Anaesth. 115(1):112-21.
Buggy DJ, Borgeat A, Cata J, Doherty DG, Doornebal CW, Forget P, Gottumukkala V, Gottschalk A, Gupta A, Gupta K et al.
. 2015.
Consensus statement from the BJA Workshop on Cancer and Anaesthesia.
.
Br J Anaesth. 114(1):2-3.
2014
Platholi J, Herold KF, Hemmings HC, Halpain S
. 2014.
Isoflurane reversibly destabilizes hippocampal dendritic spines by an actin-dependent mechanism.
.
PLoS One. 9(7):e102978.
Pryor KO, Hemmings HC
. 2014.
NAP5: intraoperative awareness detected, and undetected.
.
Br J Anaesth. 113(4):530-3.
Ingólfsson HI, Thakur P, Herold KF, E Hobart A, Ramsey NB, Periole X, de Jong DH, Zwama M, Yilmaz D, Hall K et al.
. 2014.
Phytochemicals perturb membranes and promiscuously alter protein function.
.
ACS Chem Biol. 9(8):1788-98.
Platholi J, Federman A, Detert JA, Heerdt P, Hemmings HC
. 2014.
Regulation of protein phosphatase 1I by Cdc25C-associated kinase 1 (C-TAK1) and PFTAIRE protein kinase.
.
J Biol Chem. 289(34):23893-900.
2013
Jevtovic-Todorovic V, Absalom AR, Blomgren K, Brambrink A, Crosby G, Culley DJ, Fiskum G, Giffard RG, Herold KF, Loepke AW et al.
. 2013.
Anaesthetic neurotoxicity and neuroplasticity: an expert group report and statement based on the BJA Salzburg Seminar.
.
Br J Anaesth. 111(2):143-51.
Tibbs GR, Rowley TJ, R Sanford L, Herold KF, Proekt A, Hemmings HC, Andersen OS, Goldstein PA, Flood PD
. 2013.
HCN1 channels as targets for anesthetic and nonanesthetic propofol analogs in the amelioration of mechanical and thermal hyperalgesia in a mouse model of neuropathic pain.
.
J Pharmacol Exp Ther. 345(3):363-73.
Pryor KO, Hemmings HC
. 2013.
Increased risk of awareness under anesthesia: an issue of consciousness or of memory?
Anesthesiology. 119(6):1236-8.
2009
Perouansky M, Hemmings HC
. 2009.
Between Clotho and Lachesis: how isoflurane seals neuronal fate.
.
Anesthesiology. 110(4):709-11.
Perouansky M, Hemmings HC
. 2009.
Neurotoxicity of general anesthetics: cause for concern?
Anesthesiology. 111(6):1365-71.
2008
Platholi J, Heerdt PM, Tung HYLim, Hemmings HC
. 2008.
Activation of brain protein phosphatase-1(I) following cardiac arrest and resuscitation involving an interaction with 14-3-3 gamma.
.
J Neurochem. 105(5):2029-38.
Zhang TT, Platholi J, Heerdt PM, Hemmings HC, Tung HYL
. 2008.
Protein phosphatase-2A is activated in pig brain following cardiac arrest and resuscitation.
.
Metab Brain Dis. 23(1):95-104.
2007
S Bullock A, Platholi J, Gjyrezi A, Heerdt PM, Tung HYLim, Hemmings HC
. 2007.
Differential regulation of protein phosphatase-1(I) by neurabin.
.
Biochem Biophys Res Commun. 358(1):140-4.
2006
Yun S-W, Platholi J, Flaherty MSol, Fu W, Kottmann AH, Toth M
. 2006.
Fmrp is required for the establishment of the startle response during the critical period of auditory development.
.
Brain Res. 1110(1):159-65.
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