Publications

Hemmings HC, Williams KR, Konigsberg WH, Greengard P.  1984.  DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated neuronal phosphoprotein. I. Amino acid sequence around the phosphorylated threonine.. J Biol Chem. 259(23):14486-90.

Ouimet CC, Miller PE, Hemmings HC, Walaas SI, Greengard P.  1984.  DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. III. Immunocytochemical localization.. J Neurosci. 4(1):111-24.

Williams KR, Hemmings HC, LoPresti MB, Konigsberg WH, Greengard P.  1986.  DARPP-32, a dopamine- and cyclic AMP-regulated neuronal phosphoprotein. Primary structure and homology with protein phosphatase inhibitor-1.. J Biol Chem. 261(4):1890-903.

Foster GA, Schultzberg M, Hökfelt T, Goldstein M, Hemmings HC, Ouimet CC, Walaas SI, Greengard P.  1987.  Development of a dopamine- and cyclic adenosine 3':5'-monophosphate-regulated phosphoprotein (DARPP-32) in the prenatal rat central nervous system, and its relationship to the arrival of presumptive dopaminergic innervation.. J Neurosci. 7(7):1994-2018.

Nairn AC, Hemmings HC, Walaas SI, Greengard P.  1988.  DARPP-32 and phosphatase inhibitor-1, two structurally related inhibitors of protein phosphatase-1, are both present in striatonigral neurons.. J Neurochem. 50(1):257-62.

Agnati LF, Fuxe K, Zoli M, Ferraguti F, Benfenati F, Ouimet CC, Walaas SI, Hemmings HC, Goldstein M, Greengard P.  1988.  Morphometrical evidence for a complex organization of tyrosine hydroxylase-, enkephalin- and DARPP-32-like immunoreactive patches and their codistribution at three rostrocaudal levels in the rat neostriatum.. Neuroscience. 27(3):785-97.

Foster GA, Schultzberg M, Kökfelt T, Goldstein M, Hemmings HC, Ouimet CC, Walaas SI, Greengard P.  1988.  Ontogeny of the dopamine and cyclic adenosine-3':5'-monophosphate-regulated phosphoprotein (DARPP-32) in the pre- and postnatal mouse central nervous system.. Int J Dev Neurosci. 6(4):367-86.

Williams KR, Hemmings HC, LoPresti MB, Greengard P.  1989.  ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions. I. Amino acid sequence of ARPP-21B from bovine caudate nucleus.. J Neurosci. 9(10):3631-7.

Hemmings HC, Girault JA, Williams KR, LoPresti MB, Greengard P.  1989.  ARPP-21, a cyclic AMP-regulated phosphoprotein (Mr = 21,000) enriched in dopamine-innervated brain regions. Amino acid sequence of the site phosphorylated by cyclic AMP in intact cells and kinetic studies of its phosphorylation in vitro.. J Biol Chem. 264(13):7726-33.

Girault JA, Hemmings HC, Williams KR, Nairn AC, Greengard P.  1989.  Phosphorylation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, by casein kinase II.. J Biol Chem. 264(36):21748-59.

Girault JA, Walaas SI, Hemmings HC, Greengard P.  1990.  ARPP-21, a cAMP-regulated phosphoprotein enriched in dopamine-innervated brain regions: tissue distribution and regulation of phosphorylation in rat brain.. Neuroscience. 37(2):317-25.

Wei L, Schlame M, Downes H, Hemmings HC.  1996.  CHEB, a convulsant barbiturate, evokes calcium-dependent spontaneous glutamate release from rat cerebrocortical synaptosomes.. Neuropharmacology. 35(6):695-701.

Pashkov VN, Westphalen RI, Hemmings HC.  2002.  General anesthetics do not affect release of the neuropeptide cholecystokinin from isolated rat cortical nerve terminals.. Anesthesiology. 97(6):1500-6.

Westphalen RI, Hemmings HC.  2003.  Effects of isoflurane and propofol on glutamate and GABA transporters in isolated cortical nerve terminals.. Anesthesiology. 98(2):364-72.

OuYang W, Wang G, Hemmings HC.  2003.  Isoflurane and propofol inhibit voltage-gated sodium channels in isolated rat neurohypophysial nerve terminals.. Mol Pharmacol. 64(2):373-81.

Westphalen RI, Hemmings HC.  2003.  Selective depression by general anesthetics of glutamate versus GABA release from isolated cortical nerve terminals.. J Pharmacol Exp Ther. 304(3):1188-96.

Ouyang W, Wang G, Hemmings HC.  2004.  Distinct rat neurohypophysial nerve terminal populations identified by size, electrophysiological properties and neuropeptide content.. Brain Res. 1024(1-2):203-11.

Hemmings HC, Yan W, Westphalen RI, Ryan TA.  2005.  The general anesthetic isoflurane depresses synaptic vesicle exocytosis.. Mol Pharmacol. 67(5):1591-9.

Bruening S, Oh E, Hetzenauer A, Escobar-Alvarez S, Westphalen RI, Hemmings HC, Singewald N, Shippenberg T, Toth M.  2006.  The anxiety-like phenotype of 5-HT receptor null mice is associated with genetic background-specific perturbations in the prefrontal cortex GABA-glutamate system.. J Neurochem. 99(3):892-9.

Westphalen RI, Hemmings HC.  2006.  Volatile anesthetic effects on glutamate versus GABA release from isolated rat cortical nerve terminals: basal release.. J Pharmacol Exp Ther. 316(1):208-15.

Westphalen RI, Hemmings HC.  2006.  Volatile anesthetic effects on glutamate versus GABA release from isolated rat cortical nerve terminals: 4-aminopyridine-evoked release.. J Pharmacol Exp Ther. 316(1):216-23.

Westphalen RI, Krivitski M, Amarosa A, Guy N, Hemmings HC.  2007.  Reduced inhibition of cortical glutamate and GABA release by halothane in mice lacking the K+ channel, TREK-1.. Br J Pharmacol. 152(6):939-45.

Westphalen RI, Gomez RS, Hemmings HC.  2009.  Nicotinic receptor-evoked hippocampal norepinephrine release is highly sensitive to inhibition by isoflurane.. Br J Anaesth. 102(3):355-60.

Bendor J, Lizardi-Ortiz JE, Westphalen RI, Brandstetter M, Hemmings HC, Sulzer D, Flajolet M, Greengard P.  2010.  AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release.. EMBO J. 29(16):2813-26.

Westphalen RI, Yu J, Krivitski M, Jih T-Y, Hemmings HC.  2010.  Regional differences in nerve terminal Na+ channel subtype expression and Na+ channel-dependent glutamate and GABA release in rat CNS.. J Neurochem. 113(6):1611-20.