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Interneuron diversity
Sodium channels as anesthetic targets
Volatile anesthetic effects on intracellular Ca2+ dynamics influence synaptic vesicle exocytosis
Volatile anesthetics directly bind Nav
Dr. Platholi's Research Projects
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Role of genetic polymorphisms in anesthetic-induced effects on synaptic function and structure.
Spine plasticity in anesthetic action
Voltage gated sodium channels (Nav) and hyperexcitability in early Alzheimer Disease.
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Found 17 results
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2015
Purtell K, Gingrich KJ, Ouyang W, Herold KF, Hemmings HC
. 2015.
Activity-dependent depression of neuronal sodium channels by the general anaesthetic isoflurane.
.
Br J Anaesth. 115(1):112-21.
2013
Jevtovic-Todorovic V, Absalom AR, Blomgren K, Brambrink A, Crosby G, Culley DJ, Fiskum G, Giffard RG, Herold KF, Loepke AW et al.
. 2013.
Anaesthetic neurotoxicity and neuroplasticity: an expert group report and statement based on the BJA Salzburg Seminar.
.
Br J Anaesth. 111(2):143-51.
2012
Hudetz AG, Hemmings HC
. 2012.
Anaesthesia awareness: 3 years of progress.
.
Br J Anaesth. 108(2):180-2.
2011
Hudson AE, Hemmings HC
. 2011.
Are anaesthetics toxic to the brain?
Br J Anaesth. 107(1):30-7.
2010
Bendor J, Lizardi-Ortiz JE, Westphalen RI, Brandstetter M, Hemmings HC, Sulzer D, Flajolet M, Greengard P
. 2010.
AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release.
.
EMBO J. 29(16):2813-26.
2008
Platholi J, Heerdt PM, Tung HYLim, Hemmings HC
. 2008.
Activation of brain protein phosphatase-1(I) following cardiac arrest and resuscitation involving an interaction with 14-3-3 gamma.
.
J Neurochem. 105(5):2029-38.
2006
Bruening S, Oh E, Hetzenauer A, Escobar-Alvarez S, Westphalen RI, Hemmings HC, Singewald N, Shippenberg T, Toth M
. 2006.
The anxiety-like phenotype of 5-HT receptor null mice is associated with genetic background-specific perturbations in the prefrontal cortex GABA-glutamate system.
.
J Neurochem. 99(3):892-9.
2004
Hazlett EA, Buchsbaum MS, Kemether E, Bloom R, Platholi J, Brickman AM, Shihabuddin L, Tang C, Byne W
. 2004.
Abnormal glucose metabolism in the mediodorsal nucleus of the thalamus in schizophrenia.
.
Am J Psychiatry. 161(2):305-14.
Bálint E, Kitka T, Zachar G, Adám A, Hemmings HC, Csillag A
. 2004.
Abundance and location of DARPP-32 in striato-tegmental circuits of domestic chicks.
.
J Chem Neuroanat. 28(1-2):27-36.
Perouansky M, Hemmings HC, Pearce RA
. 2004.
Anesthetic effects on glutamatergic neurotransmission: lessons learned from a large synapse.
.
Anesthesiology. 100(3):470-2.
2001
Lingamaneni R, Krasowski MD, Jenkins A, Truong T, Giunta AL, Blackbeer J, MacIver MB, Harrison NL, Hemmings HC
. 2001.
Anesthetic properties of 4-iodopropofol: implications for mechanisms of anesthesia.
.
Anesthesiology. 94(6):1050-7.
1996
Hemmings HC, Adamo AI
. 1996.
Activation of endogenous protein kinase C by halothane in synaptosomes.
.
Anesthesiology. 84(3):652-62.
1990
Girault JA, Walaas SI, Hemmings HC, Greengard P
. 1990.
ARPP-21, a cAMP-regulated phosphoprotein enriched in dopamine-innervated brain regions: tissue distribution and regulation of phosphorylation in rat brain.
.
Neuroscience. 37(2):317-25.
1989
Williams KR, Hemmings HC, LoPresti MB, Greengard P
. 1989.
ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions. I. Amino acid sequence of ARPP-21B from bovine caudate nucleus.
.
J Neurosci. 9(10):3631-7.
Hemmings HC, Greengard P
. 1989.
ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions. I. Purification and characterization of the protein from bovine caudate nucleus.
.
J Neurosci. 9(3):851-64.
Ouimet CC, Hemmings HC, Greengard P
. 1989.
ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions. II. Immunocytochemical localization in rat brain.
.
J Neurosci. 9(3):865-75.
Hemmings HC, Girault JA, Williams KR, LoPresti MB, Greengard P
. 1989.
ARPP-21, a cyclic AMP-regulated phosphoprotein (Mr = 21,000) enriched in dopamine-innervated brain regions. Amino acid sequence of the site phosphorylated by cyclic AMP in intact cells and kinetic studies of its phosphorylation in vitro.
.
J Biol Chem. 264(13):7726-33.