Publications

Hemmings HC, Nairn AC, Elliott JI, Greengard P.  1990.  Synthetic peptide analogs of DARPP-32 (Mr 32,000 dopamine- and cAMP-regulated phosphoprotein), an inhibitor of protein phosphatase-1. Phosphorylation, dephosphorylation, and inhibitory activity.. J Biol Chem. 265(33):20369-76.

Hvalby O, Hemmings HC, Paulsen O, Czernik AJ, Nairn AC, Godfraind JM, Jensen V, Raastad M, Storm JF, Andersen P.  1994.  Specificity of protein kinase inhibitor peptides and induction of long-term potentiation.. Proc Natl Acad Sci U S A. 91(11):4761-5.

Hemmings HC, Nairn AC, McGuinness TL, Huganir RL, Greengard P.  1989.  Role of protein phosphorylation in neuronal signal transduction.. FASEB J. 3(5):1583-92.

McAvoy T, Allen PB, Obaishi H, Nakanishi H, Takai Y, Greengard P, Nairn AC, Hemmings HC.  1999.  Regulation of neurabin I interaction with protein phosphatase 1 by phosphorylation.. Biochemistry. 38(39):12943-9.

Nairn AC, Hemmings HC, Greengard P.  1985.  Protein kinases in the brain.. Annu Rev Biochem. 54:931-76.

Hemmings HC, Nairn AC, Greengard P.  1986.  Protein kinases and phosphoproteins in the nervous system.. Res Publ Assoc Res Nerv Ment Dis. 64:47-69.

Bibb JA, Snyder GL, Nishi A, Yan Z, Meijer L, Fienberg AA, Tsai LH, Kwon YT, Girault JA, Czernik AJ et al..  1999.  Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons.. Nature. 402(6762):669-71.

Girault JA, Hemmings HC, Williams KR, Nairn AC, Greengard P.  1989.  Phosphorylation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, by casein kinase II.. J Biol Chem. 264(36):21748-59.

Aperia A, Fryckstedt J, Svensson L, Hemmings HC, Nairn AC, Greengard P.  1991.  Phosphorylated Mr 32,000 dopamine- and cAMP-regulated phosphoprotein inhibits Na+,K(+)-ATPase activity in renal tubule cells.. Proc Natl Acad Sci U S A. 88(7):2798-801.

Jovanovic JN, Sihra TS, Nairn AC, Hemmings HC, Greengard P, Czernik AJ.  2001.  Opposing changes in phosphorylation of specific sites in synapsin I during Ca2+-dependent glutamate release in isolated nerve terminals.. J Neurosci. 21(20):7944-53.

Surmeier DJ, Bargas J, Hemmings HC, Nairn AC, Greengard P.  1995.  Modulation of calcium currents by a D1 dopaminergic protein kinase/phosphatase cascade in rat neostriatal neurons.. Neuron. 14(2):385-97.

King MM, Huang CY, Chock PB, Nairn AC, Hemmings HC, Chan KF, Greengard P.  1984.  Mammalian brain phosphoproteins as substrates for calcineurin.. J Biol Chem. 259(13):8080-3.

Glausier JR, Maddox M, Hemmings HC, Nairn AC, Greengard P, Muly EC.  2010.  Localization of dopamine- and cAMP-regulated phosphoprotein-32 and inhibitor-1 in area 9 of Macaca mulatta prefrontal cortex.. Neuroscience. 167(2):428-38.

Gustafson EL, Girault JA, Hemmings HC, Nairn AC, Greengard P.  1991.  Immunocytochemical localization of phosphatase inhibitor-1 in rat brain.. J Comp Neurol. 310(2):170-88.

Fisone G, Cheng SX, Nairn AC, Czernik AJ, Hemmings HC, Höög JO, Bertorello AM, Kaiser R, Bergman T, Jörnvall H.  1994.  Identification of the phosphorylation site for cAMP-dependent protein kinase on Na+,K(+)-ATPase and effects of site-directed mutagenesis.. J Biol Chem. 269(12):9368-73.

Caporaso GL, Bibb JA, Snyder GL, Valle C, Rakhilin S, Fienberg AA, Hemmings HC, Nairn AC, Greengard P.  2000.  Drugs of abuse modulate the phosphorylation of ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in the basal ganglia.. Neuropharmacology. 39(9):1637-44.

Meister B, Fryckstedt J, Schalling M, Cortés R, Hökfelt T, Aperia A, Hemmings HC, Nairn AC, Ehrlich M, Greengard P.  1989.  Dopamine- and cAMP-regulated phosphoprotein (DARPP-32) and dopamine DA1 agonist-sensitive Na+,K+-ATPase in renal tubule cells.. Proc Natl Acad Sci U S A. 86(20):8068-72.

Hemmings HC, Girault JA, Nairn AC, Bertuzzi G, Greengard P.  1992.  Distribution of protein phosphatase inhibitor-1 in brain and peripheral tissues of various species: comparison with DARPP-32.. J Neurochem. 59(3):1053-61.

Nairn AC, Hemmings HC, Walaas SI, Greengard P.  1988.  DARPP-32 and phosphatase inhibitor-1, two structurally related inhibitors of protein phosphatase-1, are both present in striatonigral neurons.. J Neurochem. 50(1):257-62.

Hemmings HC, Nairn AC, Aswad DW, Greengard P.  1984.  DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. II. Purification and characterization of the phosphoprotein from bovine caudate nucleus.. J Neurosci. 4(1):99-110.

Hemmings HC, Nairn AC, Greengard P.  1984.  DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated neuronal phosphoprotein. II. Comparison of the kinetics of phosphorylation of DARPP-32 and phosphatase inhibitor 1.. J Biol Chem. 259(23):14491-7.