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Interneuron diversity
Sodium channels as anesthetic targets
Volatile anesthetic effects on intracellular Ca2+ dynamics influence synaptic vesicle exocytosis
Volatile anesthetics directly bind Nav
Dr. Platholi's Research Projects
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Role of genetic polymorphisms in anesthetic-induced effects on synaptic function and structure.
Spine plasticity in anesthetic action
Voltage gated sodium channels (Nav) and hyperexcitability in early Alzheimer Disease.
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2
Hemmings HC
,
Rosenberg AD
,
Reilly CS
,
Hunter JM
. 2010.
The 2010 BJA/PGA supplement: a selection of 10 educational reviews.
.
Br J Anaesth. 105 Suppl 1:i1-2.
Rosenberg AD
,
Hemmings HC
,
Reilly CS
,
Webster NR
. 2011.
The 2011 BJA/PGA supplement: a selection of nine educational reviews.
.
Br J Anaesth. 107 Suppl 1:i1-2.
Hemmings HC
,
Rosenberg AD
,
Mahajan RP
,
Webster NR
. 2012.
The 2012 BJA/PGA supplement: a selection of seven educational reviews.
.
Br J Anaesth. 109 Suppl 1:i1-i2.
Hemmings HC
,
Wlody D
,
Mahajan R
,
Webster NR
. 2013.
2013 BJA/PGA Special Issue: a selection of nine educational reviews.
.
Br J Anaesth. 111 Suppl 1:i1-2.
Hemmings HC
,
Wlody D
,
Mahajan R
,
Webster NR
. 2014.
The 2014 BJA/PGA special issue: a selection of six educational reviews.
.
Br J Anaesth. 113 Suppl 2:ii1-2.
Hemmings HC
,
Wlody D
,
Mahajan R
,
Webster NR
. 2015.
2015 BJA/PGA Special Issue: a selection of nine educational reviews.
.
Br J Anaesth. 115 Suppl 2:ii1-2.
Hemmings HC
,
Mahajan R
,
Webster NR
. 2016.
The 2016 BJA/PGA special issue: a selection of six educational reviews.
.
Br J Anaesth. 117(suppl 3):i1-i2.
A
Hazlett EA
,
Buchsbaum MS
,
Kemether E
,
Bloom R
,
Platholi J
,
Brickman AM
,
Shihabuddin L
,
Tang C
,
Byne W
. 2004.
Abnormal glucose metabolism in the mediodorsal nucleus of the thalamus in schizophrenia.
.
Am J Psychiatry. 161(2):305-14.
Bálint E
,
Kitka T
,
Zachar G
,
Adám A
,
Hemmings HC
,
Csillag A
. 2004.
Abundance and location of DARPP-32 in striato-tegmental circuits of domestic chicks.
.
J Chem Neuroanat. 28(1-2):27-36.
Platholi J
,
Heerdt PM
,
Tung HYLim
,
Hemmings HC
. 2008.
Activation of brain protein phosphatase-1(I) following cardiac arrest and resuscitation involving an interaction with 14-3-3 gamma.
.
J Neurochem. 105(5):2029-38.
Hemmings HC
,
Adamo AI
. 1996.
Activation of endogenous protein kinase C by halothane in synaptosomes.
.
Anesthesiology. 84(3):652-62.
Purtell K
,
Gingrich KJ
,
Ouyang W
,
Herold KF
,
Hemmings HC
. 2015.
Activity-dependent depression of neuronal sodium channels by the general anaesthetic isoflurane.
.
Br J Anaesth. 115(1):112-21.
Bendor J
,
Lizardi-Ortiz JE
,
Westphalen RI
,
Brandstetter M
,
Hemmings HC
,
Sulzer D
,
Flajolet M
,
Greengard P
. 2010.
AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release.
.
EMBO J. 29(16):2813-26.
Hudetz AG
,
Hemmings HC
. 2012.
Anaesthesia awareness: 3 years of progress.
.
Br J Anaesth. 108(2):180-2.
Jevtovic-Todorovic V
,
Absalom AR
,
Blomgren K
,
Brambrink A
,
Crosby G
,
Culley DJ
,
Fiskum G
,
Giffard RG
,
Herold KF
,
Loepke AW
et al.
. 2013.
Anaesthetic neurotoxicity and neuroplasticity: an expert group report and statement based on the BJA Salzburg Seminar.
.
Br J Anaesth. 111(2):143-51.
Perouansky M
,
Hemmings HC
,
Pearce RA
. 2004.
Anesthetic effects on glutamatergic neurotransmission: lessons learned from a large synapse.
.
Anesthesiology. 100(3):470-2.
Lingamaneni R
,
Krasowski MD
,
Jenkins A
,
Truong T
,
Giunta AL
,
Blackbeer J
,
MacIver MB
,
Harrison NL
,
Hemmings HC
. 2001.
Anesthetic properties of 4-iodopropofol: implications for mechanisms of anesthesia.
.
Anesthesiology. 94(6):1050-7.
Bruening S
,
Oh E
,
Hetzenauer A
,
Escobar-Alvarez S
,
Westphalen RI
,
Hemmings HC
,
Singewald N
,
Shippenberg T
,
Toth M
. 2006.
The anxiety-like phenotype of 5-HT receptor null mice is associated with genetic background-specific perturbations in the prefrontal cortex GABA-glutamate system.
.
J Neurochem. 99(3):892-9.
Hudson AE
,
Hemmings HC
. 2011.
Are anaesthetics toxic to the brain?
Br J Anaesth. 107(1):30-7.
Girault JA
,
Walaas SI
,
Hemmings HC
,
Greengard P
. 1990.
ARPP-21, a cAMP-regulated phosphoprotein enriched in dopamine-innervated brain regions: tissue distribution and regulation of phosphorylation in rat brain.
.
Neuroscience. 37(2):317-25.
Williams KR
,
Hemmings HC
,
LoPresti MB
,
Greengard P
. 1989.
ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions. I. Amino acid sequence of ARPP-21B from bovine caudate nucleus.
.
J Neurosci. 9(10):3631-7.
Ouimet CC
,
Hemmings HC
,
Greengard P
. 1989.
ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions. II. Immunocytochemical localization in rat brain.
.
J Neurosci. 9(3):865-75.
Hemmings HC
,
Greengard P
. 1989.
ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions. I. Purification and characterization of the protein from bovine caudate nucleus.
.
J Neurosci. 9(3):851-64.
Hemmings HC
,
Girault JA
,
Williams KR
,
LoPresti MB
,
Greengard P
. 1989.
ARPP-21, a cyclic AMP-regulated phosphoprotein (Mr = 21,000) enriched in dopamine-innervated brain regions. Amino acid sequence of the site phosphorylated by cyclic AMP in intact cells and kinetic studies of its phosphorylation in vitro.
.
J Biol Chem. 264(13):7726-33.
B
Perouansky M
,
Hemmings HC
. 2009.
Between Clotho and Lachesis: how isoflurane seals neuronal fate.
.
Anesthesiology. 110(4):709-11.
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