Publications

Hemmings HC, Girault JA, Williams KR, LoPresti MB, Greengard P.  1989.  ARPP-21, a cyclic AMP-regulated phosphoprotein (Mr = 21,000) enriched in dopamine-innervated brain regions. Amino acid sequence of the site phosphorylated by cyclic AMP in intact cells and kinetic studies of its phosphorylation in vitro.. J Biol Chem. 264(13):7726-33.

Meister B, Fryckstedt J, Schalling M, Cortés R, Hökfelt T, Aperia A, Hemmings HC, Nairn AC, Ehrlich M, Greengard P.  1989.  Dopamine- and cAMP-regulated phosphoprotein (DARPP-32) and dopamine DA1 agonist-sensitive Na+,K+-ATPase in renal tubule cells.. Proc Natl Acad Sci U S A. 86(20):8068-72.

Strålfors P, Hemmings HC, Greengard P.  1989.  Inhibitors of protein phosphatase-1. Inhibitor-1 of bovine adipose tissue and a dopamine- and cAMP-regulated phosphoprotein of bovine brain are identical.. Eur J Biochem. 180(1):143-8.

Girault JA, Hemmings HC, Williams KR, Nairn AC, Greengard P.  1989.  Phosphorylation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, by casein kinase II.. J Biol Chem. 264(36):21748-59.

Hemmings HC, Nairn AC, McGuinness TL, Huganir RL, Greengard P.  1989.  Role of protein phosphorylation in neuronal signal transduction.. FASEB J. 3(5):1583-92.

Nairn AC, Hemmings HC, Walaas SI, Greengard P.  1988.  DARPP-32 and phosphatase inhibitor-1, two structurally related inhibitors of protein phosphatase-1, are both present in striatonigral neurons.. J Neurochem. 50(1):257-62.

Hökfelt T, Foster G, Schultzberg M, Meister B, Schalling M, Goldstein M, Hemmings HC, Ouimet C, Greengard P.  1988.  DARPP-32 as a marker for D-1 dopaminoceptive cells in the rat brain: prenatal development and presence in glial elements (tanycytes) in the basal hypothalamus.. Adv Exp Med Biol. 235:65-82.

Ouimet CC, Hemmings HC, Greengard P.  1988.  Dopamine-regulated protein phosphorylation in the basal ganglia.. Adv Exp Med Biol. 235:1-17.

Meister B, Fried G, Hökfelt T, Hemmings HC, Greengard P.  1988.  Immunohistochemical evidence for the existence of a dopamine- and cyclic AMP-regulated phosphoprotein (DARPP-32) in brown adipose tissue of pigs.. Proc Natl Acad Sci U S A. 85(22):8713-6.

Agnati LF, Fuxe K, Zoli M, Ferraguti F, Benfenati F, Ouimet CC, Walaas SI, Hemmings HC, Goldstein M, Greengard P.  1988.  Morphometrical evidence for a complex organization of tyrosine hydroxylase-, enkephalin- and DARPP-32-like immunoreactive patches and their codistribution at three rostrocaudal levels in the rat neostriatum.. Neuroscience. 27(3):785-97.

Foster GA, Schultzberg M, Kökfelt T, Goldstein M, Hemmings HC, Ouimet CC, Walaas SI, Greengard P.  1988.  Ontogeny of the dopamine and cyclic adenosine-3':5'-monophosphate-regulated phosphoprotein (DARPP-32) in the pre- and postnatal mouse central nervous system.. Int J Dev Neurosci. 6(4):367-86.

Foster GA, Schultzberg M, Hökfelt T, Goldstein M, Hemmings HC, Ouimet CC, Walaas SI, Greengard P.  1987.  Development of a dopamine- and cyclic adenosine 3':5'-monophosphate-regulated phosphoprotein (DARPP-32) in the prenatal rat central nervous system, and its relationship to the arrival of presumptive dopaminergic innervation.. J Neurosci. 7(7):1994-2018.

Hemmings HC, Greengard P.  1986.  DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein: regional, tissue, and phylogenetic distribution.. J Neurosci. 6(5):1469-81.

Williams KR, Hemmings HC, LoPresti MB, Konigsberg WH, Greengard P.  1986.  DARPP-32, a dopamine- and cyclic AMP-regulated neuronal phosphoprotein. Primary structure and homology with protein phosphatase inhibitor-1.. J Biol Chem. 261(4):1890-903.

Hemmings HC, Greengard P.  1986.  DARPP-32, a dopamine-regulated phosphoprotein.. Prog Brain Res. 69:149-59.

Stone RA, Laties AM, Hemmings HC, Ouimet CC, Greengard P.  1986.  DARPP-32 in the ciliary epithelium of the eye: a neurotransmitter-regulated phosphoprotein of brain localizes to secretory cells.. J Histochem Cytochem. 34(11):1465-8.

Hemmings HC, Nairn AC, Greengard P.  1986.  Protein kinases and phosphoproteins in the nervous system.. Res Publ Assoc Res Nerv Ment Dis. 64:47-69.

Nairn AC, Hemmings HC, Greengard P.  1985.  Protein kinases in the brain.. Annu Rev Biochem. 54:931-76.

Hemmings HC, Williams KR, Konigsberg WH, Greengard P.  1984.  DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated neuronal phosphoprotein. I. Amino acid sequence around the phosphorylated threonine.. J Biol Chem. 259(23):14486-90.

Hemmings HC, Nairn AC, Greengard P.  1984.  DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated neuronal phosphoprotein. II. Comparison of the kinetics of phosphorylation of DARPP-32 and phosphatase inhibitor 1.. J Biol Chem. 259(23):14491-7.

Hemmings HC, Nairn AC, Aswad DW, Greengard P.  1984.  DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. II. Purification and characterization of the phosphoprotein from bovine caudate nucleus.. J Neurosci. 4(1):99-110.

Ouimet CC, Miller PE, Hemmings HC, Walaas SI, Greengard P.  1984.  DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. III. Immunocytochemical localization.. J Neurosci. 4(1):111-24.

Hemmings HC, Greengard P, Tung HY, Cohen P.  1984.  DARPP-32, a dopamine-regulated neuronal phosphoprotein, is a potent inhibitor of protein phosphatase-1.. Nature. 310(5977):503-5.

King MM, Huang CY, Chock PB, Nairn AC, Hemmings HC, Chan KF, Greengard P.  1984.  Mammalian brain phosphoproteins as substrates for calcineurin.. J Biol Chem. 259(13):8080-3.