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Interneuron diversity
Sodium channels as anesthetic targets
Volatile anesthetic effects on intracellular Ca2+ dynamics influence synaptic vesicle exocytosis
Volatile anesthetics directly bind Nav
Dr. Platholi's Research Projects
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Role of genetic polymorphisms in anesthetic-induced effects on synaptic function and structure.
Spine plasticity in anesthetic action
Voltage gated sodium channels (Nav) and hyperexcitability in early Alzheimer Disease.
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Found 8 results
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Year
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Membrane Potentials
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2017
Herold KF, R Sanford L, Lee W, Andersen OS, Hemmings HC
. 2017.
Clinical concentrations of chemically diverse general anesthetics minimally affect lipid bilayer properties.
.
Proc Natl Acad Sci U S A. 114(12):3109-3114.
2015
Purtell K, Gingrich KJ, Ouyang W, Herold KF, Hemmings HC
. 2015.
Activity-dependent depression of neuronal sodium channels by the general anaesthetic isoflurane.
.
Br J Anaesth. 115(1):112-21.
2011
Rusinova R, Herold KF, R Sanford L, Greathouse DV, Hemmings HC, Andersen OS
. 2011.
Thiazolidinedione insulin sensitizers alter lipid bilayer properties and voltage-dependent sodium channel function: implications for drug discovery.
.
J Gen Physiol. 138(2):249-70.
2007
OuYang W, Hemmings HC
. 2007.
Isoform-selective effects of isoflurane on voltage-gated Na+ channels.
.
Anesthesiology. 107(1):91-8.
2005
OuYang W, Hemmings HC
. 2005.
Depression by isoflurane of the action potential and underlying voltage-gated ion currents in isolated rat neurohypophysial nerve terminals.
.
J Pharmacol Exp Ther. 312(2):801-8.
2000
Ratnakumari L, Vysotskaya TN, Duch DS, Hemmings HC
. 2000.
Differential effects of anesthetic and nonanesthetic cyclobutanes on neuronal voltage-gated sodium channels.
.
Anesthesiology. 92(2):529-41.
Lingameneni R, Vysotskaya TN, Duch DS, Hemmings HC
. 2000.
Inhibition of voltage-dependent sodium channels by Ro 31-8220, a 'specific' protein kinase C inhibitor.
.
FEBS Lett. 473(2):265-8.
1995
Surmeier DJ, Bargas J, Hemmings HC, Nairn AC, Greengard P
. 1995.
Modulation of calcium currents by a D1 dopaminergic protein kinase/phosphatase cascade in rat neostriatal neurons.
.
Neuron. 14(2):385-97.