Publications

Herold KF, R Sanford L, Lee W, Andersen OS, Hemmings HC.  2017.  Clinical concentrations of chemically diverse general anesthetics minimally affect lipid bilayer properties.. Proc Natl Acad Sci U S A. 114(12):3109-3114.

Herold KF, Andersen OS, Hemmings HC.  2017.  Divergent effects of anesthetics on lipid bilayer properties and sodium channel function.. Eur Biophys J. 46(7):617-626.

Sand RM, Gingrich KJ, Macharadze T, Herold KF, Hemmings HC.  2017.  Isoflurane modulates activation and inactivation gating of the prokaryotic Na channel NaChBac.. J Gen Physiol. 149(6):623-638.

Johnson KW, Herold KF, Milner TA, Hemmings HC, Platholi J.  2017.  Sodium channel subtypes are differentially localized to pre- and post-synaptic sites in rat hippocampus.. J Comp Neurol. 525(16):3563-3578.

Riegelhaupt PM, Hemmings HC, Goldstein PA.  2016.  Relevance of Clinical Relevance.. Anesthesiology. 125(4):821-2.

Hara M, Zhou Z-Y, Hemmings HC.  2016.  α2-Adrenergic Receptor and Isoflurane Modulation of Presynaptic Ca2+ Influx and Exocytosis in Hippocampal Neurons.. Anesthesiology. 125(3):535-46.

Baumgart JP, Zhou Z-Y, Hara M, Cook DC, Hoppa MB, Ryan TA, Hemmings HC.  2015.  Isoflurane inhibits synaptic vesicle exocytosis through reduced Ca2+ influx, not Ca2+-exocytosis coupling.. Proc Natl Acad Sci U S A. 112(38):11959-64.

Platholi J, Herold KF, Hemmings HC, Halpain S.  2014.  Isoflurane reversibly destabilizes hippocampal dendritic spines by an actin-dependent mechanism.. PLoS One. 9(7):e102978.

Ingólfsson HI, Thakur P, Herold KF, E Hobart A, Ramsey NB, Periole X, de Jong DH, Zwama M, Yilmaz D, Hall K et al..  2014.  Phytochemicals perturb membranes and promiscuously alter protein function.. ACS Chem Biol. 9(8):1788-98.

Platholi J, Federman A, Detert JA, Heerdt P, Hemmings HC.  2014.  Regulation of protein phosphatase 1I by Cdc25C-associated kinase 1 (C-TAK1) and PFTAIRE protein kinase.. J Biol Chem. 289(34):23893-900.

Huang V, Hemmings HC, Crews D.  2014.  Sociosexual investigation in sexually experienced, hormonally manipulated male leopard geckos: relation with phosphorylated DARPP-32 in dopaminergic pathways.. J Exp Zool A Ecol Genet Physiol. 321(10):595-602.

Herold KF, R Sanford L, Lee W, Schultz MF, Ingólfsson HI, Andersen OS, Hemmings HC.  2014.  Volatile anesthetics inhibit sodium channels without altering bulk lipid bilayer properties.. J Gen Physiol. 144(6):545-60.

Tibbs GR, Rowley TJ, R Sanford L, Herold KF, Proekt A, Hemmings HC, Andersen OS, Goldstein PA, Flood PD.  2013.  HCN1 channels as targets for anesthetic and nonanesthetic propofol analogs in the amelioration of mechanical and thermal hyperalgesia in a mouse model of neuropathic pain.. J Pharmacol Exp Ther. 345(3):363-73.

Pryor KO, Hemmings HC.  2013.  Increased risk of awareness under anesthesia: an issue of consciousness or of memory? Anesthesiology. 119(6):1236-8.

Herold KF, Hemmings HC.  2012.  Sodium channels as targets for volatile anesthetics.. Front Pharmacol. 3:50.

Westphalen RI, Kwak N-B, Daniels K, Hemmings HC.  2011.  Regional differences in the effects of isoflurane on neurotransmitter release.. Neuropharmacology. 61(4):699-706.

Hemmings HC, Mackie K.  2011.  The rivers of Lethe and Mnemosyne converge: propofol and memory consolidation.. Anesthesiology. 114(6):1277-9.

Mantz J, Hemmings HC.  2011.  Sleep and anesthesia: the histamine connection.. Anesthesiology. 115(1):8-9.

Rusinova R, Herold KF, R Sanford L, Greathouse DV, Hemmings HC, Andersen OS.  2011.  Thiazolidinedione insulin sensitizers alter lipid bilayer properties and voltage-dependent sodium channel function: implications for drug discovery.. J Gen Physiol. 138(2):249-70.

Hemmings HC, Rosenberg AD, Reilly CS, Hunter JM.  2010.  The 2010 BJA/PGA supplement: a selection of 10 educational reviews.. Br J Anaesth. 105 Suppl 1:i1-2.

Bendor J, Lizardi-Ortiz JE, Westphalen RI, Brandstetter M, Hemmings HC, Sulzer D, Flajolet M, Greengard P.  2010.  AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release.. EMBO J. 29(16):2813-26.

Mantz J, Hemmings HC, Boddaert J.  2010.  Case scenario: postoperative delirium in elderly surgical patients.. Anesthesiology. 112(1):189-95.

Hemmings HC, Greengard P.  2010.  Positively active: how local anesthetics work.. Anesthesiology. 113(1):250-2.

Westphalen RI, Yu J, Krivitski M, Jih T-Y, Hemmings HC.  2010.  Regional differences in nerve terminal Na+ channel subtype expression and Na+ channel-dependent glutamate and GABA release in rat CNS.. J Neurochem. 113(6):1611-20.

Perouansky M, Hemmings HC.  2009.  Between Clotho and Lachesis: how isoflurane seals neuronal fate.. Anesthesiology. 110(4):709-11.