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Interneuron diversity
Sodium channels as anesthetic targets
Volatile anesthetic effects on intracellular Ca2+ dynamics influence synaptic vesicle exocytosis
Volatile anesthetics directly bind Nav
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Role of genetic polymorphisms in anesthetic-induced effects on synaptic function and structure.
Spine plasticity in anesthetic action
Voltage gated sodium channels (Nav) and hyperexcitability in early Alzheimer Disease.
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X
Y
Z
G
Girault JA
,
Hemmings HC
,
Zorn SH
,
Gustafson EL
,
Greengard P
. 1990.
Characterization in mammalian brain of a DARPP-32 serine kinase identical to casein kinase II.
.
J Neurochem. 55(5):1772-83.
Girault JA
,
Hemmings HC
,
Williams KR
,
Nairn AC
,
Greengard P
. 1989.
Phosphorylation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, by casein kinase II.
.
J Biol Chem. 264(36):21748-59.
Girault JA
,
Walaas SI
,
Hemmings HC
,
Greengard P
. 1990.
ARPP-21, a cAMP-regulated phosphoprotein enriched in dopamine-innervated brain regions: tissue distribution and regulation of phosphorylation in rat brain.
.
Neuroscience. 37(2):317-25.
Glausier JR
,
Maddox M
,
Hemmings HC
,
Nairn AC
,
Greengard P
,
Muly EC
. 2010.
Localization of dopamine- and cAMP-regulated phosphoprotein-32 and inhibitor-1 in area 9 of Macaca mulatta prefrontal cortex.
.
Neuroscience. 167(2):428-38.
Gustafson EL
,
Girault JA
,
Hemmings HC
,
Nairn AC
,
Greengard P
. 1991.
Immunocytochemical localization of phosphatase inhibitor-1 in rat brain.
.
J Comp Neurol. 310(2):170-88.
H
Hara M
,
Zhou Z-Y
,
Hemmings HC
. 2016.
α2-Adrenergic Receptor and Isoflurane Modulation of Presynaptic Ca2+ Influx and Exocytosis in Hippocampal Neurons.
.
Anesthesiology. 125(3):535-46.
Hazlett EA
,
Buchsbaum MS
,
Hsieh P
,
M Haznedar M
,
Platholi J
,
LiCalzi EM
,
Cartwright C
,
Hollander E
. 2004.
Regional glucose metabolism within cortical Brodmann areas in healthy individuals and autistic patients.
.
Neuropsychobiology. 49(3):115-25.
Hazlett EA
,
Buchsbaum MS
,
Kemether E
,
Bloom R
,
Platholi J
,
Brickman AM
,
Shihabuddin L
,
Tang C
,
Byne W
. 2004.
Abnormal glucose metabolism in the mediodorsal nucleus of the thalamus in schizophrenia.
.
Am J Psychiatry. 161(2):305-14.
Hemmings HC
,
Greengard P
,
Tung HY
,
Cohen P
. 1984.
DARPP-32, a dopamine-regulated neuronal phosphoprotein, is a potent inhibitor of protein phosphatase-1.
.
Nature. 310(5977):503-5.
Hemmings HC
,
Wlody D
,
Mahajan R
,
Webster NR
. 2014.
The 2014 BJA/PGA special issue: a selection of six educational reviews.
.
Br J Anaesth. 113 Suppl 2:ii1-2.
Hemmings HC
. 2009.
Sodium channels and the synaptic mechanisms of inhaled anaesthetics.
.
Br J Anaesth. 103(1):61-9.
Hemmings HC
. 2007.
Noble meets nouveau: a shared anesthetic binding site for xenon and isoflurane on a glutamate receptor.
.
Anesthesiology. 107(5):694-6.
Hemmings HC
,
Wlody D
,
Mahajan R
,
Webster NR
. 2015.
2015 BJA/PGA Special Issue: a selection of nine educational reviews.
.
Br J Anaesth. 115 Suppl 2:ii1-2.
Hemmings HC
,
Lambert DG
. 2019.
The good, the bad, and the ugly: the many faces of opioids.
.
Br J Anaesth. 122(6):705-707.
Hemmings HC
. 2017.
A global vision for the British Journal of Anaesthesia.
.
Br J Anaesth. 118(1):1-2.
Hemmings HC
,
Flood P
. 2008.
Galloping in full pursuit of the mechanism of anesthetic immobility.
.
Anesthesiology. 108(6):975-6.
Hemmings HC
,
Greengard P
. 1986.
DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein: regional, tissue, and phylogenetic distribution.
.
J Neurosci. 6(5):1469-81.
Hemmings HC
,
Yan W
,
Westphalen RI
,
Ryan TA
. 2005.
The general anesthetic isoflurane depresses synaptic vesicle exocytosis.
.
Mol Pharmacol. 67(5):1591-9.
Hemmings HC
,
Hunter JM
. 2017.
Landmarks in UK anaesthesia.
.
Br J Anaesth. 119(6):1073-1074.
Hemmings HC
,
Greengard P
. 2010.
Positively active: how local anesthetics work.
.
Anesthesiology. 113(1):250-2.
Hemmings HC
,
Jevtovic-Todorovic V
. 2013.
Special issue on anaesthetic neurotoxicity and neuroplasticity.
.
Br J Anaesth. 110 Suppl 1:i1-2.
Hemmings HC
,
Girault JA
,
Nairn AC
,
Bertuzzi G
,
Greengard P
. 1992.
Distribution of protein phosphatase inhibitor-1 in brain and peripheral tissues of various species: comparison with DARPP-32.
.
J Neurochem. 59(3):1053-61.
Hemmings HC
,
Riegelhaupt PM
,
Kelz MB
,
Solt K
,
Eckenhoff RG
,
Orser BA
,
Goldstein PA
. 2019.
Towards a Comprehensive Understanding of Anesthetic Mechanisms of Action: A Decade of Discovery.
.
Trends Pharmacol Sci. 40(7):464-481.
Hemmings HC
. 1998.
General anesthetic effects on protein kinase C.
.
Toxicol Lett. 100-101:89-95.
Hemmings HC
,
Nairn AC
,
McGuinness TL
,
Huganir RL
,
Greengard P
. 1989.
Role of protein phosphorylation in neuronal signal transduction.
.
FASEB J. 3(5):1583-92.
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