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Interneuron diversity
Sodium channels as anesthetic targets
Volatile anesthetic effects on intracellular Ca2+ dynamics influence synaptic vesicle exocytosis
Volatile anesthetics directly bind Nav
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Role of genetic polymorphisms in anesthetic-induced effects on synaptic function and structure.
Spine plasticity in anesthetic action
Voltage gated sodium channels (Nav) and hyperexcitability in early Alzheimer Disease.
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Platholi, Jimcy
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Platholi J, Federman A, Detert JA, Heerdt P, Hemmings HC
. 2014.
Regulation of protein phosphatase 1I by Cdc25C-associated kinase 1 (C-TAK1) and PFTAIRE protein kinase.
.
J Biol Chem. 289(34):23893-900.
Platholi J, Herold KF, Hemmings HC, Halpain S
. 2014.
Isoflurane reversibly destabilizes hippocampal dendritic spines by an actin-dependent mechanism.
.
PLoS One. 9(7):e102978.
Platholi J, Heerdt PM, Tung HYLim, Hemmings HC
. 2008.
Activation of brain protein phosphatase-1(I) following cardiac arrest and resuscitation involving an interaction with 14-3-3 gamma.
.
J Neurochem. 105(5):2029-38.
Platholi J, Hemmings HC
. 2021.
Modulation of dendritic spines by protein phosphatase-1.
.
Adv Pharmacol. 90:117-144.
Platholi J, Hemmings HC
. 2022.
Effects of General Anesthetics on Synaptic Transmission and Plasticity.
.
Curr Neuropharmacol. 20(1):27-54.
