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Interneuron diversity
Sodium channels as anesthetic targets
Volatile anesthetic effects on intracellular Ca2+ dynamics influence synaptic vesicle exocytosis
Volatile anesthetics directly bind Nav
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Role of genetic polymorphisms in anesthetic-induced effects on synaptic function and structure.
Spine plasticity in anesthetic action
Voltage gated sodium channels (Nav) and hyperexcitability in early Alzheimer Disease.
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H
Hemmings HC
. 2019.
Change management: the British Journal of Anaesthesia in 2018.
.
Br J Anaesth. 122(1):1-3.
Hemmings HC
,
Nairn AC
,
Greengard P
. 1984.
DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated neuronal phosphoprotein. II. Comparison of the kinetics of phosphorylation of DARPP-32 and phosphatase inhibitor 1.
.
J Biol Chem. 259(23):14491-7.
Hemmings HC
,
Mackie K
. 2011.
The rivers of Lethe and Mnemosyne converge: propofol and memory consolidation.
.
Anesthesiology. 114(6):1277-9.
Hemmings HC
. 2004.
Neuroprotection by Na+ channel blockade.
.
J Neurosurg Anesthesiol. 16(1):100-1.
Hemmings HC
,
Adamo AI
. 1996.
Activation of endogenous protein kinase C by halothane in synaptosomes.
.
Anesthesiology. 84(3):652-62.
Hemmings HC
,
Adamo AI
. 1997.
Effect of halothane on conventional protein kinase C translocation and down-regulation in rat cerebrocortical synaptosomes.
.
Br J Anaesth. 78(2):189-96.
Hemmings HC
,
Nairn AC
,
Elliott JI
,
Greengard P
. 1990.
Synthetic peptide analogs of DARPP-32 (Mr 32,000 dopamine- and cAMP-regulated phosphoprotein), an inhibitor of protein phosphatase-1. Phosphorylation, dephosphorylation, and inhibitory activity.
.
J Biol Chem. 265(33):20369-76.
Hemmings HC
,
Rosenberg AD
,
Mahajan RP
,
Webster NR
. 2012.
The 2012 BJA/PGA supplement: a selection of seven educational reviews.
.
Br J Anaesth. 109 Suppl 1:i1-i2.
Hemmings HC
,
Nairn AC
,
Aswad DW
,
Greengard P
. 1984.
DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. II. Purification and characterization of the phosphoprotein from bovine caudate nucleus.
.
J Neurosci. 4(1):99-110.
Hemmings HC
,
Akabas MH
,
Goldstein PA
,
Trudell JR
,
Orser BA
,
Harrison NL
. 2005.
Emerging molecular mechanisms of general anesthetic action.
.
Trends Pharmacol Sci. 26(10):503-10.
Hemmings HC
,
Shafer SL
. 2020.
Further retractions of articles by Joachim Boldt.
.
Br J Anaesth. 125(3):409-411.
Hemmings HC
,
Mahajan R
,
Webster NR
. 2016.
The 2016 BJA/PGA special issue: a selection of six educational reviews.
.
Br J Anaesth. 117(suppl 3):i1-i2.
Hemmings HC
,
Adamo AI
. 1994.
Effects of halothane and propofol on purified brain protein kinase C activation.
.
Anesthesiology. 81(1):147-55.
Hemmings HC
,
Greengard P
. 1986.
DARPP-32, a dopamine-regulated phosphoprotein.
.
Prog Brain Res. 69:149-59.
Hemmings HC
,
Williams KR
,
Konigsberg WH
,
Greengard P
. 1984.
DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated neuronal phosphoprotein. I. Amino acid sequence around the phosphorylated threonine.
.
J Biol Chem. 259(23):14486-90.
Hemmings HC
,
Antognini JF
. 2006.
Do general anesthetics add up?
Anesthesiology. 104(6):1120-2.
Hemmings HC
,
Wlody D
,
Mahajan R
,
Webster NR
. 2013.
2013 BJA/PGA Special Issue: a selection of nine educational reviews.
.
Br J Anaesth. 111 Suppl 1:i1-2.
Hemmings HC
,
Greengard P
. 1989.
ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions. I. Purification and characterization of the protein from bovine caudate nucleus.
.
J Neurosci. 9(3):851-64.
Hemmings HC
,
Rosenberg AD
,
Reilly CS
,
Hunter JM
. 2010.
The 2010 BJA/PGA supplement: a selection of 10 educational reviews.
.
Br J Anaesth. 105 Suppl 1:i1-2.
Hemmings HC
,
Adamo AI
,
Hoffman MM
. 1995.
Biochemical characterization of the stimulatory effects of halothane and propofol on purified brain protein kinase C.
.
Anesth Analg. 81(6):1216-22.
Hemmings HC
,
Mantz J
. 2008.
Xenon and the pharmacology of fear.
.
Anesthesiology. 109(6):954-5.
Hemmings HC
,
Nairn AC
,
Greengard P
. 1986.
Protein kinases and phosphoproteins in the nervous system.
.
Res Publ Assoc Res Nerv Ment Dis. 64:47-69.
Hemmings HC
,
Girault JA
,
Williams KR
,
LoPresti MB
,
Greengard P
. 1989.
ARPP-21, a cyclic AMP-regulated phosphoprotein (Mr = 21,000) enriched in dopamine-innervated brain regions. Amino acid sequence of the site phosphorylated by cyclic AMP in intact cells and kinetic studies of its phosphorylation in vitro.
.
J Biol Chem. 264(13):7726-33.
Herold KF
,
R Sanford L
,
Lee W
,
Schultz MF
,
Ingólfsson HI
,
Andersen OS
,
Hemmings HC
. 2014.
Volatile anesthetics inhibit sodium channels without altering bulk lipid bilayer properties.
.
J Gen Physiol. 144(6):545-60.
Herold KF
,
R Sanford L
,
Lee W
,
Andersen OS
,
Hemmings HC
. 2017.
Clinical concentrations of chemically diverse general anesthetics minimally affect lipid bilayer properties.
.
Proc Natl Acad Sci U S A. 114(12):3109-3114.
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