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Interneuron diversity
Sodium channels as anesthetic targets
Volatile anesthetic effects on intracellular Ca2+ dynamics influence synaptic vesicle exocytosis
Volatile anesthetics directly bind Nav
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Role of genetic polymorphisms in anesthetic-induced effects on synaptic function and structure.
Spine plasticity in anesthetic action
Voltage gated sodium channels (Nav) and hyperexcitability in early Alzheimer Disease.
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Hemmings HC, Akabas MH, Goldstein PA, Trudell JR, Orser BA, Harrison NL
. 2005.
Emerging molecular mechanisms of general anesthetic action.
.
Trends Pharmacol Sci. 26(10):503-10.
H
Tibbs GR, Rowley TJ, R Sanford L, Herold KF, Proekt A, Hemmings HC, Andersen OS, Goldstein PA, Flood PD
. 2013.
HCN1 channels as targets for anesthetic and nonanesthetic propofol analogs in the amelioration of mechanical and thermal hyperalgesia in a mouse model of neuropathic pain.
.
J Pharmacol Exp Ther. 345(3):363-73.
R
Riegelhaupt PM, Hemmings HC, Goldstein PA
. 2016.
Relevance of Clinical Relevance.
.
Anesthesiology. 125(4):821-2.
T
Hemmings HC, Riegelhaupt PM, Kelz MB, Solt K, Eckenhoff RG, Orser BA, Goldstein PA
. 2019.
Towards a Comprehensive Understanding of Anesthetic Mechanisms of Action: A Decade of Discovery.
.
Trends Pharmacol Sci. 40(7):464-481.
