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Interneuron diversity
Sodium channels as anesthetic targets
Volatile anesthetic effects on intracellular Ca2+ dynamics influence synaptic vesicle exocytosis
Volatile anesthetics directly bind Nav
Dr. Platholi's Research Projects
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Role of genetic polymorphisms in anesthetic-induced effects on synaptic function and structure.
Spine plasticity in anesthetic action
Voltage gated sodium channels (Nav) and hyperexcitability in early Alzheimer Disease.
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Author
Title
Type
Year
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I
J
K
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P
Q
R
S
T
U
V
W
X
Y
Z
S
Hvalby O
,
Hemmings HC
,
Paulsen O
,
Czernik AJ
,
Nairn AC
,
Godfraind JM
,
Jensen V
,
Raastad M
,
Storm JF
,
Andersen P
. 1994.
Specificity of protein kinase inhibitor peptides and induction of long-term potentiation.
.
Proc Natl Acad Sci U S A. 91(11):4761-5.
Chang S
,
Hemmings HC
,
Aderem A
. 1996.
Stimulus-dependent phosphorylation of MacMARCKS, a protein kinase C substrate, in nerve termini and PC12 cells.
.
J Biol Chem. 271(2):1174-8.
Hemmings HC
,
Nairn AC
,
Elliott JI
,
Greengard P
. 1990.
Synthetic peptide analogs of DARPP-32 (Mr 32,000 dopamine- and cAMP-regulated phosphoprotein), an inhibitor of protein phosphatase-1. Phosphorylation, dephosphorylation, and inhibitory activity.
.
J Biol Chem. 265(33):20369-76.
T
Rusinova R
,
Herold KF
,
R Sanford L
,
Greathouse DV
,
Hemmings HC
,
Andersen OS
. 2011.
Thiazolidinedione insulin sensitizers alter lipid bilayer properties and voltage-dependent sodium channel function: implications for drug discovery.
.
J Gen Physiol. 138(2):249-70.
Soriano SG
,
Vutskits L
,
Jevtovic-Todorovic V
,
Hemmings HC
. 2017.
Thinking, fast and slow: highlights from the 2016 BJA seminar on anaesthetic neurotoxicity and neuroplasticity.
.
Br J Anaesth. 119(3):443-447.
Kaur G
,
Pryor KO
,
Milewski AR
,
Weinberg R
,
Hemmings HC
. 2023.
Torture mechanisms and chronic somatic pain in US refugees.
.
Br J Anaesth. 131(2):e41-e43.
Hemmings HC
,
Riegelhaupt PM
,
Kelz MB
,
Solt K
,
Eckenhoff RG
,
Orser BA
,
Goldstein PA
. 2019.
Towards a Comprehensive Understanding of Anesthetic Mechanisms of Action: A Decade of Discovery.
.
Trends Pharmacol Sci. 40(7):464-481.
Hemmings HC
. 2022.
Turning the page on 2021: an eventful year for the British Journal of Anaesthesia.
.
Br J Anaesth. 128(1):1-3.
V
Fu D
,
Vissavajjhala P
,
Hemmings HC
. 2005.
Volatile anaesthetic effects on phospholipid binding to synaptotagmin 1, a presynaptic Ca2+ sensor.
.
Br J Anaesth. 95(2):216-21.
Westphalen RI
,
Hemmings HC
. 2006.
Volatile anesthetic effects on glutamate versus GABA release from isolated rat cortical nerve terminals: 4-aminopyridine-evoked release.
.
J Pharmacol Exp Ther. 316(1):216-23.
Westphalen RI
,
Hemmings HC
. 2006.
Volatile anesthetic effects on glutamate versus GABA release from isolated rat cortical nerve terminals: basal release.
.
J Pharmacol Exp Ther. 316(1):208-15.
Herold KF
,
R Sanford L
,
Lee W
,
Schultz MF
,
Ingólfsson HI
,
Andersen OS
,
Hemmings HC
. 2014.
Volatile anesthetics inhibit sodium channels without altering bulk lipid bilayer properties.
.
J Gen Physiol. 144(6):545-60.
W
Lingamaneni R
,
Birch ML
,
Hemmings HC
. 2001.
Widespread inhibition of sodium channel-dependent glutamate release from isolated nerve terminals by isoflurane and propofol.
.
Anesthesiology. 95(6):1460-6.
Wong CA
,
S Moonesinghe R
,
Boer C
,
Hemmings HC
,
Hunter JM
. 2020.
Women in anaesthesia, a special issue of the British Journal of Anaesthesia.
.
Br J Anaesth. 124(3):e40-e43.
X
Hemmings HC
,
Mantz J
. 2008.
Xenon and the pharmacology of fear.
.
Anesthesiology. 109(6):954-5.
Α
Hara M
,
Zhou Z-Y
,
Hemmings HC
. 2016.
α2-Adrenergic Receptor and Isoflurane Modulation of Presynaptic Ca2+ Influx and Exocytosis in Hippocampal Neurons.
.
Anesthesiology. 125(3):535-46.
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