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Interneuron diversity
Sodium channels as anesthetic targets
Volatile anesthetic effects on intracellular Ca2+ dynamics influence synaptic vesicle exocytosis
Volatile anesthetics directly bind Nav
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Role of genetic polymorphisms in anesthetic-induced effects on synaptic function and structure.
Spine plasticity in anesthetic action
Voltage gated sodium channels (Nav) and hyperexcitability in early Alzheimer Disease.
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Found 21 results
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2021
Zhao W, Zhao S, Zhu T, Ou M, Zhang D, Sun H, Liu J, Chen X, Hemmings HC, Zhou C
. 2021.
Isoflurane Suppresses Hippocampal High-frequency Ripples by Differentially Modulating Pyramidal Neurons and Interneurons in Mice.
.
Anesthesiology. 135(1):122-135.
Zhao W, Zhao S, Zhu T, Ou M, Zhang D, Sun H, Liu J, Chen X, Hemmings HC, Zhou C
. 2021.
Isoflurane Suppresses Hippocampal High-frequency Ripples by Differentially Modulating Pyramidal Neurons and Interneurons in Mice.
.
Anesthesiology. 135(1):122-135.
Zhao W, Zhao S, Zhu T, Ou M, Zhang D, Sun H, Liu J, Chen X, Hemmings HC, Zhou C
. 2021.
Isoflurane Suppresses Hippocampal High-frequency Ripples by Differentially Modulating Pyramidal Neurons and Interneurons in Mice.
.
Anesthesiology. 135(1):122-135.
Zhao W, Zhao S, Zhu T, Ou M, Zhang D, Sun H, Liu J, Chen X, Hemmings HC, Zhou C
. 2021.
Isoflurane Suppresses Hippocampal High-frequency Ripples by Differentially Modulating Pyramidal Neurons and Interneurons in Mice.
.
Anesthesiology. 135(1):122-135.
Zhao W, Zhao S, Zhu T, Ou M, Zhang D, Sun H, Liu J, Chen X, Hemmings HC, Zhou C
. 2021.
Isoflurane Suppresses Hippocampal High-frequency Ripples by Differentially Modulating Pyramidal Neurons and Interneurons in Mice.
.
Anesthesiology. 135(1):122-135.
2019
Zhou C, Johnson KW, Herold KF, Hemmings HC
. 2019.
Differential Inhibition of Neuronal Sodium Channel Subtypes by the General Anesthetic Isoflurane.
.
J Pharmacol Exp Ther. 369(2):200-211.
Torturo CL, Zhou Z-Y, Ryan TA, Hemmings HC
. 2019.
Isoflurane Inhibits Dopaminergic Synaptic Vesicle Exocytosis Coupled to Ca2.1 and Ca2.2 in Rat Midbrain Neurons.
.
eNeuro. 6(1)
Zhao W, Zhang M, Liu J, Liang P, Wang R, Hemmings HC, Zhou C
. 2019.
Isoflurane Modulates Hippocampal Cornu Ammonis Pyramidal Neuron Excitability by Inhibition of Both Transient and Persistent Sodium Currents in Mice.
.
Anesthesiology. 131(1):94-104.
Zhao W, Zhang M, Liu J, Liang P, Wang R, Hemmings HC, Zhou C
. 2019.
Isoflurane Modulates Hippocampal Cornu Ammonis Pyramidal Neuron Excitability by Inhibition of Both Transient and Persistent Sodium Currents in Mice.
.
Anesthesiology. 131(1):94-104.
Zhao W, Zhang M, Liu J, Liang P, Wang R, Hemmings HC, Zhou C
. 2019.
Isoflurane Modulates Hippocampal Cornu Ammonis Pyramidal Neuron Excitability by Inhibition of Both Transient and Persistent Sodium Currents in Mice.
.
Anesthesiology. 131(1):94-104.
Koyanagi Y, Torturo CL, Cook DC, Zhou Z, Hemmings HC
. 2019.
Role of specific presynaptic calcium channel subtypes in isoflurane inhibition of synaptic vesicle exocytosis in rat hippocampal neurones.
.
Br J Anaesth. 123(2):219-227.
2016
Hara M, Zhou Z-Y, Hemmings HC
. 2016.
α2-Adrenergic Receptor and Isoflurane Modulation of Presynaptic Ca2+ Influx and Exocytosis in Hippocampal Neurons.
.
Anesthesiology. 125(3):535-46.
2015
Baumgart JP, Zhou Z-Y, Hara M, Cook DC, Hoppa MB, Ryan TA, Hemmings HC
. 2015.
Isoflurane inhibits synaptic vesicle exocytosis through reduced Ca2+ influx, not Ca2+-exocytosis coupling.
.
Proc Natl Acad Sci U S A. 112(38):11959-64.
2014
Ingólfsson HI, Thakur P, Herold KF, E Hobart A, Ramsey NB, Periole X, de Jong DH, Zwama M, Yilmaz D, Hall K et al.
. 2014.
Phytochemicals perturb membranes and promiscuously alter protein function.
.
ACS Chem Biol. 9(8):1788-98.
2010
Zhang Y, Guzinski M, Eger EI, Laster MJ, Sharma M, Harris RA, Hemmings HC
. 2010.
Bidirectional modulation of isoflurane potency by intrathecal tetrodotoxin and veratridine in rats.
.
Br J Pharmacol. 159(4):872-8.
2008
Zhang Y, Sharma M, Eger EI, Laster MJ, Hemmings HC, R Harris A
. 2008.
Intrathecal veratridine administration increases minimum alveolar concentration in rats.
.
Anesth Analg. 107(3):875-8.
Zhang TT, Platholi J, Heerdt PM, Hemmings HC, Tung HYL
. 2008.
Protein phosphatase-2A is activated in pig brain following cardiac arrest and resuscitation.
.
Metab Brain Dis. 23(1):95-104.
2007
OuYang W, Jih T-Y, Zhang T-T, Correa AM, Hemmings HC
. 2007.
Isoflurane inhibits NaChBac, a prokaryotic voltage-gated sodium channel.
.
J Pharmacol Exp Ther. 322(3):1076-83.
2004
Bálint E, Kitka T, Zachar G, Adám A, Hemmings HC, Csillag A
. 2004.
Abundance and location of DARPP-32 in striato-tegmental circuits of domestic chicks.
.
J Chem Neuroanat. 28(1-2):27-36.
1990
Girault JA, Hemmings HC, Zorn SH, Gustafson EL, Greengard P
. 1990.
Characterization in mammalian brain of a DARPP-32 serine kinase identical to casein kinase II.
.
J Neurochem. 55(5):1772-83.
1988
Agnati LF, Fuxe K, Zoli M, Ferraguti F, Benfenati F, Ouimet CC, Walaas SI, Hemmings HC, Goldstein M, Greengard P
. 1988.
Morphometrical evidence for a complex organization of tyrosine hydroxylase-, enkephalin- and DARPP-32-like immunoreactive patches and their codistribution at three rostrocaudal levels in the rat neostriatum.
.
Neuroscience. 27(3):785-97.