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Interneuron diversity
Sodium channels as anesthetic targets
Volatile anesthetic effects on intracellular Ca2+ dynamics influence synaptic vesicle exocytosis
Volatile anesthetics directly bind Nav
Dr. Platholi's Research Projects
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Role of genetic polymorphisms in anesthetic-induced effects on synaptic function and structure.
Spine plasticity in anesthetic action
Voltage gated sodium channels (Nav) and hyperexcitability in early Alzheimer Disease.
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Found 191 results
Author
Title
Type
Year
1997
Schnabel R
,
Metzger M
,
Jiang S
,
Hemmings HC
,
Greengard P
,
Braun K
. 1997.
Localization of dopamine D1 receptors and dopaminoceptive neurons in the chick forebrain.
.
J Comp Neurol. 388(1):146-68.
1998
Durstewitz D
,
Kröner S
,
Hemmings HC
,
Güntürkün O
. 1998.
The dopaminergic innervation of the pigeon telencephalon: distribution of DARPP-32 and co-occurrence with glutamate decarboxylase and tyrosine hydroxylase.
.
Neuroscience. 83(3):763-79.
Murugaiah KD
,
Hemmings HC
. 1998.
Effects of intravenous general anesthetics on [3H]GABA release from rat cortical synaptosomes.
.
Anesthesiology. 89(4):919-28.
Hemmings HC
. 1998.
General anesthetic effects on protein kinase C.
.
Toxicol Lett. 100-101:89-95.
Ratnakumari L
,
Hemmings HC
. 1998.
Inhibition of presynaptic sodium channels by halothane.
.
Anesthesiology. 88(4):1043-54.
1999
Lingamaneni R
,
Hemmings HC
. 1999.
Effects of anticonvulsants on veratridine- and KCl-evoked glutamate release from rat cortical synaptosomes.
.
Neurosci Lett. 276(2):127-30.
Mayerhofer A
,
Hemmings HC
,
Snyder GL
,
Greengard P
,
Boddien S
,
Berg U
,
Brucker C
. 1999.
Functional dopamine-1 receptors and DARPP-32 are expressed in human ovary and granulosa luteal cells in vitro.
.
J Clin Endocrinol Metab. 84(1):257-64.
Bibb JA
,
Snyder GL
,
Nishi A
,
Yan Z
,
Meijer L
,
Fienberg AA
,
Tsai LH
,
Kwon YT
,
Girault JA
,
Czernik AJ
et al.
. 1999.
Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons.
.
Nature. 402(6762):669-71.
McAvoy T
,
Allen PB
,
Obaishi H
,
Nakanishi H
,
Takai Y
,
Greengard P
,
Nairn AC
,
Hemmings HC
. 1999.
Regulation of neurabin I interaction with protein phosphatase 1 by phosphorylation.
.
Biochemistry. 38(39):12943-9.
2000
Ratnakumari L
,
Vysotskaya TN
,
Duch DS
,
Hemmings HC
. 2000.
Differential effects of anesthetic and nonanesthetic cyclobutanes on neuronal voltage-gated sodium channels.
.
Anesthesiology. 92(2):529-41.
Caporaso GL
,
Bibb JA
,
Snyder GL
,
Valle C
,
Rakhilin S
,
Fienberg AA
,
Hemmings HC
,
Nairn AC
,
Greengard P
. 2000.
Drugs of abuse modulate the phosphorylation of ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in the basal ganglia.
.
Neuropharmacology. 39(9):1637-44.
Lingameneni R
,
Vysotskaya TN
,
Duch DS
,
Hemmings HC
. 2000.
Inhibition of voltage-dependent sodium channels by Ro 31-8220, a 'specific' protein kinase C inhibitor.
.
FEBS Lett. 473(2):265-8.
2001
Lingamaneni R
,
Krasowski MD
,
Jenkins A
,
Truong T
,
Giunta AL
,
Blackbeer J
,
MacIver MB
,
Harrison NL
,
Hemmings HC
. 2001.
Anesthetic properties of 4-iodopropofol: implications for mechanisms of anesthesia.
.
Anesthesiology. 94(6):1050-7.
Absil P
,
Foidart A
,
Hemmings HC
,
Steinbusch HW
,
Ball GF
,
Balthazart J
. 2001.
Distribution of DARPP-32 immunoreactive structures in the quail brain: anatomical relationship with dopamine and aromatase.
.
J Chem Neuroanat. 21(1):23-39.
Jovanovic JN
,
Sihra TS
,
Nairn AC
,
Hemmings HC
,
Greengard P
,
Czernik AJ
. 2001.
Opposing changes in phosphorylation of specific sites in synapsin I during Ca2+-dependent glutamate release in isolated nerve terminals.
.
J Neurosci. 21(20):7944-53.
Lingamaneni R
,
Birch ML
,
Hemmings HC
. 2001.
Widespread inhibition of sodium channel-dependent glutamate release from isolated nerve terminals by isoflurane and propofol.
.
Anesthesiology. 95(6):1460-6.
2002
New AS
,
Hazlett EA
,
Buchsbaum MS
,
Goodman M
,
Reynolds D
,
Mitropoulou V
,
Sprung L
,
Shaw RB
,
Koenigsberg H
,
Platholi J
et al.
. 2002.
Blunted prefrontal cortical 18fluorodeoxyglucose positron emission tomography response to meta-chlorophenylpiperazine in impulsive aggression.
.
Arch Gen Psychiatry. 59(7):621-9.
Pashkov VN
,
Hemmings HC
. 2002.
The effects of general anesthetics on norepinephrine release from isolated rat cortical nerve terminals.
.
Anesth Analg. 95(5):1274-81,tableofcontents.
Albert KA
,
Hemmings HC
,
Adamo AIB
,
Potkin SG
,
Akbarian S
,
Sandman CA
,
Cotman CW
,
Bunney WE
,
Greengard P
. 2002.
Evidence for decreased DARPP-32 in the prefrontal cortex of patients with schizophrenia.
.
Arch Gen Psychiatry. 59(8):705-12.
Shahani SK
,
Lingamaneni R
,
Hemmings HC
. 2002.
General anesthetic actions on norepinephrine, dopamine, and gamma-aminobutyric acid transporters in stably transfected cells.
.
Anesth Analg. 95(4):893-9,tableofcontents.
Pashkov VN
,
Westphalen RI
,
Hemmings HC
. 2002.
General anesthetics do not affect release of the neuropeptide cholecystokinin from isolated rat cortical nerve terminals.
.
Anesthesiology. 97(6):1500-6.
2003
Lingamaneni R
,
Hemmings HC
. 2003.
Differential interaction of anaesthetics and antiepileptic drugs with neuronal Na+ channels, Ca2+ channels, and GABA(A) receptors.
.
Br J Anaesth. 90(2):199-211.
Westphalen RI
,
Hemmings HC
. 2003.
Effects of isoflurane and propofol on glutamate and GABA transporters in isolated cortical nerve terminals.
.
Anesthesiology. 98(2):364-72.
OuYang W
,
Wang G
,
Hemmings HC
. 2003.
Isoflurane and propofol inhibit voltage-gated sodium channels in isolated rat neurohypophysial nerve terminals.
.
Mol Pharmacol. 64(2):373-81.
Kemether EM
,
Buchsbaum MS
,
Byne W
,
Hazlett EA
,
Haznedar M
,
Brickman AM
,
Platholi J
,
Bloom R
. 2003.
Magnetic resonance imaging of mediodorsal, pulvinar, and centromedian nuclei of the thalamus in patients with schizophrenia.
.
Arch Gen Psychiatry. 60(10):983-91.
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