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Interneuron diversity
Sodium channels as anesthetic targets
Volatile anesthetic effects on intracellular Ca2+ dynamics influence synaptic vesicle exocytosis
Volatile anesthetics directly bind Nav
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Role of genetic polymorphisms in anesthetic-induced effects on synaptic function and structure.
Spine plasticity in anesthetic action
Voltage gated sodium channels (Nav) and hyperexcitability in early Alzheimer Disease.
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Found 84 results
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Hemmings, Hugh C
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Hara M
,
Zhou Z-Y
,
Hemmings HC
. 2016.
α2-Adrenergic Receptor and Isoflurane Modulation of Presynaptic Ca2+ Influx and Exocytosis in Hippocampal Neurons.
.
Anesthesiology. 125(3):535-46.
X
Hemmings HC
,
Mantz J
. 2008.
Xenon and the pharmacology of fear.
.
Anesthesiology. 109(6):954-5.
W
Wong CA
,
S Moonesinghe R
,
Boer C
,
Hemmings HC
,
Hunter JM
. 2020.
Women in anaesthesia, a special issue of the British Journal of Anaesthesia.
.
Br J Anaesth. 124(3):e40-e43.
V
Herold KF
,
R Sanford L
,
Lee W
,
Schultz MF
,
Ingólfsson HI
,
Andersen OS
,
Hemmings HC
. 2014.
Volatile anesthetics inhibit sodium channels without altering bulk lipid bilayer properties.
.
J Gen Physiol. 144(6):545-60.
Westphalen RI
,
Hemmings HC
. 2006.
Volatile anesthetic effects on glutamate versus GABA release from isolated rat cortical nerve terminals: basal release.
.
J Pharmacol Exp Ther. 316(1):208-15.
Westphalen RI
,
Hemmings HC
. 2006.
Volatile anesthetic effects on glutamate versus GABA release from isolated rat cortical nerve terminals: 4-aminopyridine-evoked release.
.
J Pharmacol Exp Ther. 316(1):216-23.
T
Hemmings HC
. 2022.
Turning the page on 2021: an eventful year for the British Journal of Anaesthesia.
.
Br J Anaesth. 128(1):1-3.
Hemmings HC
,
Riegelhaupt PM
,
Kelz MB
,
Solt K
,
Eckenhoff RG
,
Orser BA
,
Goldstein PA
. 2019.
Towards a Comprehensive Understanding of Anesthetic Mechanisms of Action: A Decade of Discovery.
.
Trends Pharmacol Sci. 40(7):464-481.
Kaur G
,
Pryor KO
,
Milewski AR
,
Weinberg R
,
Hemmings HC
. 2023.
Torture mechanisms and chronic somatic pain in US refugees.
.
Br J Anaesth. 131(2):e41-e43.
Rusinova R
,
Herold KF
,
R Sanford L
,
Greathouse DV
,
Hemmings HC
,
Andersen OS
. 2011.
Thiazolidinedione insulin sensitizers alter lipid bilayer properties and voltage-dependent sodium channel function: implications for drug discovery.
.
J Gen Physiol. 138(2):249-70.
S
Asai T
,
O'Sullivan EP
,
Hemmings HC
. 2020.
A special issue on respiration and the airway: critical topics at a challenging time.
.
Br J Anaesth. 125(1):1-4.
Herold KF
,
Hemmings HC
. 2012.
Sodium channels as targets for volatile anesthetics.
.
Front Pharmacol. 3:50.
Johnson KW
,
Herold KF
,
Milner TA
,
Hemmings HC
,
Platholi J
. 2017.
Sodium channel subtypes are differentially localized to pre- and post-synaptic sites in rat hippocampus.
.
J Comp Neurol. 525(16):3563-3578.
Huang V
,
Hemmings HC
,
Crews D
. 2014.
Sociosexual investigation in sexually experienced, hormonally manipulated male leopard geckos: relation with phosphorylated DARPP-32 in dopaminergic pathways.
.
J Exp Zool A Ecol Genet Physiol. 321(10):595-602.
Mantz J
,
Hemmings HC
. 2011.
Sleep and anesthesia: the histamine connection.
.
Anesthesiology. 115(1):8-9.
Speigel IA
,
Hemmings HC
. 2021.
Selective inhibition of gamma aminobutyric acid release from mouse hippocampal interneurone subtypes by the volatile anaesthetic isoflurane.
.
Br J Anaesth. 127(4):587-599.
Westphalen RI
,
Hemmings HC
. 2003.
Selective depression by general anesthetics of glutamate versus GABA release from isolated cortical nerve terminals.
.
J Pharmacol Exp Ther. 304(3):1188-96.
R
Koyanagi Y
,
Torturo CL
,
Cook DC
,
Zhou Z
,
Hemmings HC
. 2019.
Role of specific presynaptic calcium channel subtypes in isoflurane inhibition of synaptic vesicle exocytosis in rat hippocampal neurones.
.
Br J Anaesth. 123(2):219-227.
Hemmings HC
,
Mackie K
. 2011.
The rivers of Lethe and Mnemosyne converge: propofol and memory consolidation.
.
Anesthesiology. 114(6):1277-9.
Speigel IA
,
Hemmings HC
. 2021.
Relevance of Cortical and Hippocampal Interneuron Functional Diversity to General Anesthetic Mechanisms: A Narrative Review.
.
Front Synaptic Neurosci. 13:812905.
Riegelhaupt PM
,
Hemmings HC
,
Goldstein PA
. 2016.
Relevance of Clinical Relevance.
.
Anesthesiology. 125(4):821-2.
Nguyen C
,
Nishi A
,
Kansy JW
,
Fernandez J
,
Hayashi K
,
Gillardon F
,
Hemmings HC
,
Nairn AC
,
Bibb JA
. 2007.
Regulation of protein phosphatase inhibitor-1 by cyclin-dependent kinase 5.
.
J Biol Chem. 282(22):16511-20.
Platholi J
,
Federman A
,
Detert JA
,
Heerdt P
,
Hemmings HC
. 2014.
Regulation of protein phosphatase 1I by Cdc25C-associated kinase 1 (C-TAK1) and PFTAIRE protein kinase.
.
J Biol Chem. 289(34):23893-900.
Westphalen RI
,
Kwak N-B
,
Daniels K
,
Hemmings HC
. 2011.
Regional differences in the effects of isoflurane on neurotransmitter release.
.
Neuropharmacology. 61(4):699-706.
Westphalen RI
,
Yu J
,
Krivitski M
,
Jih T-Y
,
Hemmings HC
. 2010.
Regional differences in nerve terminal Na+ channel subtype expression and Na+ channel-dependent glutamate and GABA release in rat CNS.
.
J Neurochem. 113(6):1611-20.
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