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Interneuron diversity
Sodium channels as anesthetic targets
Volatile anesthetic effects on intracellular Ca2+ dynamics influence synaptic vesicle exocytosis
Volatile anesthetics directly bind Nav
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Role of genetic polymorphisms in anesthetic-induced effects on synaptic function and structure.
Spine plasticity in anesthetic action
Voltage gated sodium channels (Nav) and hyperexcitability in early Alzheimer Disease.
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Found 84 results
Author
Title
Type
Year
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Hemmings, Hugh C
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2002
Pashkov VN
,
Hemmings HC
. 2002.
The effects of general anesthetics on norepinephrine release from isolated rat cortical nerve terminals.
.
Anesth Analg. 95(5):1274-81,tableofcontents.
Albert KA
,
Hemmings HC
,
Adamo AIB
,
Potkin SG
,
Akbarian S
,
Sandman CA
,
Cotman CW
,
Bunney WE
,
Greengard P
. 2002.
Evidence for decreased DARPP-32 in the prefrontal cortex of patients with schizophrenia.
.
Arch Gen Psychiatry. 59(8):705-12.
Shahani SK
,
Lingamaneni R
,
Hemmings HC
. 2002.
General anesthetic actions on norepinephrine, dopamine, and gamma-aminobutyric acid transporters in stably transfected cells.
.
Anesth Analg. 95(4):893-9,tableofcontents.
Pashkov VN
,
Westphalen RI
,
Hemmings HC
. 2002.
General anesthetics do not affect release of the neuropeptide cholecystokinin from isolated rat cortical nerve terminals.
.
Anesthesiology. 97(6):1500-6.
2003
Westphalen RI
,
Hemmings HC
. 2003.
Effects of isoflurane and propofol on glutamate and GABA transporters in isolated cortical nerve terminals.
.
Anesthesiology. 98(2):364-72.
OuYang W
,
Wang G
,
Hemmings HC
. 2003.
Isoflurane and propofol inhibit voltage-gated sodium channels in isolated rat neurohypophysial nerve terminals.
.
Mol Pharmacol. 64(2):373-81.
Westphalen RI
,
Hemmings HC
. 2003.
Selective depression by general anesthetics of glutamate versus GABA release from isolated cortical nerve terminals.
.
J Pharmacol Exp Ther. 304(3):1188-96.
2004
Perouansky M
,
Hemmings HC
,
Pearce RA
. 2004.
Anesthetic effects on glutamatergic neurotransmission: lessons learned from a large synapse.
.
Anesthesiology. 100(3):470-2.
Hemmings HC
. 2004.
Neuroprotection by Na+ channel blockade.
.
J Neurosurg Anesthesiol. 16(1):100-1.
Morrow PW
,
Tung HYLim
,
Hemmings HC
. 2004.
Rapamycin causes activation of protein phosphatase-2A1 and nuclear translocation of PCNA in CD4+ T cells.
.
Biochem Biophys Res Commun. 323(2):645-51.
2005
OuYang W
,
Hemmings HC
. 2005.
Depression by isoflurane of the action potential and underlying voltage-gated ion currents in isolated rat neurohypophysial nerve terminals.
.
J Pharmacol Exp Ther. 312(2):801-8.
Hemmings HC
,
Akabas MH
,
Goldstein PA
,
Trudell JR
,
Orser BA
,
Harrison NL
. 2005.
Emerging molecular mechanisms of general anesthetic action.
.
Trends Pharmacol Sci. 26(10):503-10.
Hemmings HC
,
Yan W
,
Westphalen RI
,
Ryan TA
. 2005.
The general anesthetic isoflurane depresses synaptic vesicle exocytosis.
.
Mol Pharmacol. 67(5):1591-9.
Futter M
,
Uematsu K
,
Bullock SA
,
Kim Y
,
Hemmings HC
,
Nishi A
,
Greengard P
,
Nairn AC
. 2005.
Phosphorylation of spinophilin by ERK and cyclin-dependent PK 5 (Cdk5).
.
Proc Natl Acad Sci U S A. 102(9):3489-94.
2006
Hotte M
,
Thuault S
,
Lachaise F
,
Dineley KT
,
Hemmings HC
,
Nairn AC
,
Jay TM
. 2006.
D1 receptor modulation of memory retrieval performance is associated with changes in pCREB and pDARPP-32 in rat prefrontal cortex.
.
Behav Brain Res. 171(1):127-33.
Hemmings HC
,
Antognini JF
. 2006.
Do general anesthetics add up?
Anesthesiology. 104(6):1120-2.
Westphalen RI
,
Hemmings HC
. 2006.
Volatile anesthetic effects on glutamate versus GABA release from isolated rat cortical nerve terminals: basal release.
.
J Pharmacol Exp Ther. 316(1):208-15.
Westphalen RI
,
Hemmings HC
. 2006.
Volatile anesthetic effects on glutamate versus GABA release from isolated rat cortical nerve terminals: 4-aminopyridine-evoked release.
.
J Pharmacol Exp Ther. 316(1):216-23.
2007
S Bullock A
,
Platholi J
,
Gjyrezi A
,
Heerdt PM
,
Tung HYLim
,
Hemmings HC
. 2007.
Differential regulation of protein phosphatase-1(I) by neurabin.
.
Biochem Biophys Res Commun. 358(1):140-4.
Snyder GL
,
Galdi S
,
Hendrick JP
,
Hemmings HC
. 2007.
General anesthetics selectively modulate glutamatergic and dopaminergic signaling via site-specific phosphorylation in vivo.
.
Neuropharmacology. 53(5):619-30.
OuYang W
,
Jih T-Y
,
Zhang T-T
,
Correa AM
,
Hemmings HC
. 2007.
Isoflurane inhibits NaChBac, a prokaryotic voltage-gated sodium channel.
.
J Pharmacol Exp Ther. 322(3):1076-83.
OuYang W
,
Hemmings HC
. 2007.
Isoform-selective effects of isoflurane on voltage-gated Na+ channels.
.
Anesthesiology. 107(1):91-8.
Hemmings HC
. 2007.
Noble meets nouveau: a shared anesthetic binding site for xenon and isoflurane on a glutamate receptor.
.
Anesthesiology. 107(5):694-6.
Hotte M
,
Thuault S
,
Dineley KT
,
Hemmings HC
,
Nairn AC
,
Jay TM
. 2007.
Phosphorylation of CREB and DARPP-32 during late LTP at hippocampal to prefrontal cortex synapses in vivo.
.
Synapse. 61(1):24-8.
Nguyen C
,
Nishi A
,
Kansy JW
,
Fernandez J
,
Hayashi K
,
Gillardon F
,
Hemmings HC
,
Nairn AC
,
Bibb JA
. 2007.
Regulation of protein phosphatase inhibitor-1 by cyclin-dependent kinase 5.
.
J Biol Chem. 282(22):16511-20.
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