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Interneuron diversity
Sodium channels as anesthetic targets
Volatile anesthetic effects on intracellular Ca2+ dynamics influence synaptic vesicle exocytosis
Volatile anesthetics directly bind Nav
Dr. Platholi's Research Projects
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Role of genetic polymorphisms in anesthetic-induced effects on synaptic function and structure.
Spine plasticity in anesthetic action
Voltage gated sodium channels (Nav) and hyperexcitability in early Alzheimer Disease.
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Found 9 results
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Year
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Cells, Cultured
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2019
Torturo CL, Zhou Z-Y, Ryan TA, Hemmings HC
. 2019.
Isoflurane Inhibits Dopaminergic Synaptic Vesicle Exocytosis Coupled to Ca2.1 and Ca2.2 in Rat Midbrain Neurons.
.
eNeuro. 6(1)
Koyanagi Y, Torturo CL, Cook DC, Zhou Z, Hemmings HC
. 2019.
Role of specific presynaptic calcium channel subtypes in isoflurane inhibition of synaptic vesicle exocytosis in rat hippocampal neurones.
.
Br J Anaesth. 123(2):219-227.
2017
Johnson KW, Herold KF, Milner TA, Hemmings HC, Platholi J
. 2017.
Sodium channel subtypes are differentially localized to pre- and post-synaptic sites in rat hippocampus.
.
J Comp Neurol. 525(16):3563-3578.
2015
Purtell K, Gingrich KJ, Ouyang W, Herold KF, Hemmings HC
. 2015.
Activity-dependent depression of neuronal sodium channels by the general anaesthetic isoflurane.
.
Br J Anaesth. 115(1):112-21.
2010
Bendor J, Lizardi-Ortiz JE, Westphalen RI, Brandstetter M, Hemmings HC, Sulzer D, Flajolet M, Greengard P
. 2010.
AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release.
.
EMBO J. 29(16):2813-26.
2007
OuYang W, Hemmings HC
. 2007.
Isoform-selective effects of isoflurane on voltage-gated Na+ channels.
.
Anesthesiology. 107(1):91-8.
2005
Hemmings HC, Yan W, Westphalen RI, Ryan TA
. 2005.
The general anesthetic isoflurane depresses synaptic vesicle exocytosis.
.
Mol Pharmacol. 67(5):1591-9.
1999
Mayerhofer A, Hemmings HC, Snyder GL, Greengard P, Boddien S, Berg U, Brucker C
. 1999.
Functional dopamine-1 receptors and DARPP-32 are expressed in human ovary and granulosa luteal cells in vitro.
.
J Clin Endocrinol Metab. 84(1):257-64.
1995
Surmeier DJ, Bargas J, Hemmings HC, Nairn AC, Greengard P
. 1995.
Modulation of calcium currents by a D1 dopaminergic protein kinase/phosphatase cascade in rat neostriatal neurons.
.
Neuron. 14(2):385-97.