Publications

Girault JA, Hemmings HC, Williams KR, Nairn AC, Greengard P.  1989.  Phosphorylation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, by casein kinase II.. J Biol Chem. 264(36):21748-59.

Hemmings HC, Nairn AC, McGuinness TL, Huganir RL, Greengard P.  1989.  Role of protein phosphorylation in neuronal signal transduction.. FASEB J. 3(5):1583-92.

Girault JA, Walaas SI, Hemmings HC, Greengard P.  1990.  ARPP-21, a cAMP-regulated phosphoprotein enriched in dopamine-innervated brain regions: tissue distribution and regulation of phosphorylation in rat brain.. Neuroscience. 37(2):317-25.

Girault JA, Hemmings HC, Zorn SH, Gustafson EL, Greengard P.  1990.  Characterization in mammalian brain of a DARPP-32 serine kinase identical to casein kinase II.. J Neurochem. 55(5):1772-83.

Hemmings HC, Nairn AC, Elliott JI, Greengard P.  1990.  Synthetic peptide analogs of DARPP-32 (Mr 32,000 dopamine- and cAMP-regulated phosphoprotein), an inhibitor of protein phosphatase-1. Phosphorylation, dephosphorylation, and inhibitory activity.. J Biol Chem. 265(33):20369-76.

Meister B, Schultzberg M, Hemmings HC, Greengard P, Goldstein M, Hökfelt T.  1991.  Dopamine- and adenosine-3',5'-monophosphate (cAMP)-regulated phosphoprotein of 32 kDa (DARPP-32) in the adrenal gland: immunohistochemical localization.. J Auton Nerv Syst. 36(1):75-84.

Meister B, Arvidsson U, Hemmings HC, Greengard P, Hökfelt T.  1991.  Dopamine- and adenosine-3':5'-monophosphate (cAMP)-regulated phosphoprotein of Mr 32,000 (DARPP-32) in the retina of cat, monkey and human.. Neurosci Lett. 131(1):66-70.

Meister B, Askergren J, Tunevall G, Hemmings HC, Greengard P.  1991.  Identification of a dopamine- and 3'5'-cyclic adenosine monophosphate-regulated phosphoprotein of 32 kD (DARPP-32) in parathyroid hormone-producing cells of the human parathyroid gland.. J Endocrinol Invest. 14(8):655-61.

Gustafson EL, Girault JA, Hemmings HC, Nairn AC, Greengard P.  1991.  Immunocytochemical localization of phosphatase inhibitor-1 in rat brain.. J Comp Neurol. 310(2):170-88.

Aperia A, Fryckstedt J, Svensson L, Hemmings HC, Nairn AC, Greengard P.  1991.  Phosphorylated Mr 32,000 dopamine- and cAMP-regulated phosphoprotein inhibits Na+,K(+)-ATPase activity in renal tubule cells.. Proc Natl Acad Sci U S A. 88(7):2798-801.

Hemmings HC, Girault JA, Nairn AC, Bertuzzi G, Greengard P.  1992.  Distribution of protein phosphatase inhibitor-1 in brain and peripheral tissues of various species: comparison with DARPP-32.. J Neurochem. 59(3):1053-61.

Hemmings HC, Adamo AI.  1994.  Effects of halothane and propofol on purified brain protein kinase C activation.. Anesthesiology. 81(1):147-55.

Fisone G, Cheng SX, Nairn AC, Czernik AJ, Hemmings HC, Höög JO, Bertorello AM, Kaiser R, Bergman T, Jörnvall H.  1994.  Identification of the phosphorylation site for cAMP-dependent protein kinase on Na+,K(+)-ATPase and effects of site-directed mutagenesis.. J Biol Chem. 269(12):9368-73.

Hvalby O, Hemmings HC, Paulsen O, Czernik AJ, Nairn AC, Godfraind JM, Jensen V, Raastad M, Storm JF, Andersen P.  1994.  Specificity of protein kinase inhibitor peptides and induction of long-term potentiation.. Proc Natl Acad Sci U S A. 91(11):4761-5.

Hemmings HC, Adamo AI, Hoffman MM.  1995.  Biochemical characterization of the stimulatory effects of halothane and propofol on purified brain protein kinase C.. Anesth Analg. 81(6):1216-22.

Matovcik LM, Hemmings HC, Kinder BK.  1995.  DARPP-32 (dopamine and cAMP-regulated phosphoprotein, M(r) 32,000) is a membrane protein in the bovine parathyroid.. FEBS Lett. 364(1):67-74.

Schlame M, Hemmings HC.  1995.  Inhibition by volatile anesthetics of endogenous glutamate release from synaptosomes by a presynaptic mechanism.. Anesthesiology. 82(6):1406-16.

Surmeier DJ, Bargas J, Hemmings HC, Nairn AC, Greengard P.  1995.  Modulation of calcium currents by a D1 dopaminergic protein kinase/phosphatase cascade in rat neostriatal neurons.. Neuron. 14(2):385-97.

Hemmings HC, Adamo AI.  1996.  Activation of endogenous protein kinase C by halothane in synaptosomes.. Anesthesiology. 84(3):652-62.

Wei L, Schlame M, Downes H, Hemmings HC.  1996.  CHEB, a convulsant barbiturate, evokes calcium-dependent spontaneous glutamate release from rat cerebrocortical synaptosomes.. Neuropharmacology. 35(6):695-701.

Lien CA, Hemmings HC, Belmont MR, Abalos A, Hollmann C, Kelly RE.  1996.  A comparison: the efficacy of sevoflurane-nitrous oxide or propofol-nitrous oxide for the induction and maintenance of general anesthesia.. J Clin Anesth. 8(8):639-43.

Ratnakumari L, Hemmings HC.  1996.  Inhibition by propofol of [3H]-batrachotoxinin-A 20-alpha-benzoate binding to voltage-dependent sodium channels in rat cortical synaptosomes.. Br J Pharmacol. 119(7):1498-504.

Chang S, Hemmings HC, Aderem A.  1996.  Stimulus-dependent phosphorylation of MacMARCKS, a protein kinase C substrate, in nerve termini and PC12 cells.. J Biol Chem. 271(2):1174-8.

Hemmings HC, Adamo AI.  1997.  Effect of halothane on conventional protein kinase C translocation and down-regulation in rat cerebrocortical synaptosomes.. Br J Anaesth. 78(2):189-96.

Ratnakumari L, Hemmings HC.  1997.  Effects of propofol on sodium channel-dependent sodium influx and glutamate release in rat cerebrocortical synaptosomes.. Anesthesiology. 86(2):428-39.