Publications

Torturo CL, Zhou Z-Y, Ryan TA, Hemmings HC.  2019.  Isoflurane Inhibits Dopaminergic Synaptic Vesicle Exocytosis Coupled to Ca2.1 and Ca2.2 in Rat Midbrain Neurons.. eNeuro. 6(1)

Koyanagi Y, Torturo CL, Cook DC, Zhou Z, Hemmings HC.  2019.  Role of specific presynaptic calcium channel subtypes in isoflurane inhibition of synaptic vesicle exocytosis in rat hippocampal neurones.. Br J Anaesth. 123(2):219-227.

Ingólfsson HI, Thakur P, Herold KF, E Hobart A, Ramsey NB, Periole X, de Jong DH, Zwama M, Yilmaz D, Hall K et al..  2014.  Phytochemicals perturb membranes and promiscuously alter protein function.. ACS Chem Biol. 9(8):1788-98.

Tibbs GR, Rowley TJ, R Sanford L, Herold KF, Proekt A, Hemmings HC, Andersen OS, Goldstein PA, Flood PD.  2013.  HCN1 channels as targets for anesthetic and nonanesthetic propofol analogs in the amelioration of mechanical and thermal hyperalgesia in a mouse model of neuropathic pain.. J Pharmacol Exp Ther. 345(3):363-73.

Twersky RS, Hemmings HC.  2009.  Introduction: 2009 BJA/PGA Supplement: a selection of eight reviews.. Br J Anaesth. 103 Suppl 1:i1-2.

Platholi J, Heerdt PM, Tung HYLim, Hemmings HC.  2008.  Activation of brain protein phosphatase-1(I) following cardiac arrest and resuscitation involving an interaction with 14-3-3 gamma.. J Neurochem. 105(5):2029-38.

Zhang TT, Platholi J, Heerdt PM, Hemmings HC, Tung HYL.  2008.  Protein phosphatase-2A is activated in pig brain following cardiac arrest and resuscitation.. Metab Brain Dis. 23(1):95-104.

S Bullock A, Platholi J, Gjyrezi A, Heerdt PM, Tung HYLim, Hemmings HC.  2007.  Differential regulation of protein phosphatase-1(I) by neurabin.. Biochem Biophys Res Commun. 358(1):140-4.

Hotte M, Thuault S, Dineley KT, Hemmings HC, Nairn AC, Jay TM.  2007.  Phosphorylation of CREB and DARPP-32 during late LTP at hippocampal to prefrontal cortex synapses in vivo.. Synapse. 61(1):24-8.

Bruening S, Oh E, Hetzenauer A, Escobar-Alvarez S, Westphalen RI, Hemmings HC, Singewald N, Shippenberg T, Toth M.  2006.  The anxiety-like phenotype of 5-HT receptor null mice is associated with genetic background-specific perturbations in the prefrontal cortex GABA-glutamate system.. J Neurochem. 99(3):892-9.

Hotte M, Thuault S, Lachaise F, Dineley KT, Hemmings HC, Nairn AC, Jay TM.  2006.  D1 receptor modulation of memory retrieval performance is associated with changes in pCREB and pDARPP-32 in rat prefrontal cortex.. Behav Brain Res. 171(1):127-33.

Yun S-W, Platholi J, Flaherty MSol, Fu W, Kottmann AH, Toth M.  2006.  Fmrp is required for the establishment of the startle response during the critical period of auditory development.. Brain Res. 1110(1):159-65.

Hemmings HC, Akabas MH, Goldstein PA, Trudell JR, Orser BA, Harrison NL.  2005.  Emerging molecular mechanisms of general anesthetic action.. Trends Pharmacol Sci. 26(10):503-10.

Hazlett EA, Buchsbaum MS, Kemether E, Bloom R, Platholi J, Brickman AM, Shihabuddin L, Tang C, Byne W.  2004.  Abnormal glucose metabolism in the mediodorsal nucleus of the thalamus in schizophrenia.. Am J Psychiatry. 161(2):305-14.

Morrow PW, Tung HYLim, Hemmings HC.  2004.  Rapamycin causes activation of protein phosphatase-2A1 and nuclear translocation of PCNA in CD4+ T cells.. Biochem Biophys Res Commun. 323(2):645-51.

Lingamaneni R, Krasowski MD, Jenkins A, Truong T, Giunta AL, Blackbeer J, MacIver MB, Harrison NL, Hemmings HC.  2001.  Anesthetic properties of 4-iodopropofol: implications for mechanisms of anesthesia.. Anesthesiology. 94(6):1050-7.

Bibb JA, Snyder GL, Nishi A, Yan Z, Meijer L, Fienberg AA, Tsai LH, Kwon YT, Girault JA, Czernik AJ et al..  1999.  Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons.. Nature. 402(6762):669-71.

McAvoy T, Allen PB, Obaishi H, Nakanishi H, Takai Y, Greengard P, Nairn AC, Hemmings HC.  1999.  Regulation of neurabin I interaction with protein phosphatase 1 by phosphorylation.. Biochemistry. 38(39):12943-9.

Meister B, Askergren J, Tunevall G, Hemmings HC, Greengard P.  1991.  Identification of a dopamine- and 3'5'-cyclic adenosine monophosphate-regulated phosphoprotein of 32 kD (DARPP-32) in parathyroid hormone-producing cells of the human parathyroid gland.. J Endocrinol Invest. 14(8):655-61.

Hemmings HC, Greengard P, Tung HY, Cohen P.  1984.  DARPP-32, a dopamine-regulated neuronal phosphoprotein, is a potent inhibitor of protein phosphatase-1.. Nature. 310(5977):503-5.