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Interneuron diversity
Sodium channels as anesthetic targets
Volatile anesthetic effects on intracellular Ca2+ dynamics influence synaptic vesicle exocytosis
Volatile anesthetics directly bind Nav
Dr. Platholi's Research Projects
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Role of genetic polymorphisms in anesthetic-induced effects on synaptic function and structure.
Spine plasticity in anesthetic action
Voltage gated sodium channels (Nav) and hyperexcitability in early Alzheimer Disease.
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Found 191 results
Author
Title
Type
Year
2006
Buchsbaum MS
,
Hollander E
,
Pallanti S
,
Rossi NBaldini
,
Platholi J
,
Newmark R
,
Bloom R
,
Sood E
. 2006.
Positron emission tomography imaging of risperidone augmentation in serotonin reuptake inhibitor-refractory patients.
.
Neuropsychobiology. 53(3):157-68.
Westphalen RI
,
Hemmings HC
. 2006.
Volatile anesthetic effects on glutamate versus GABA release from isolated rat cortical nerve terminals: 4-aminopyridine-evoked release.
.
J Pharmacol Exp Ther. 316(1):216-23.
Westphalen RI
,
Hemmings HC
. 2006.
Volatile anesthetic effects on glutamate versus GABA release from isolated rat cortical nerve terminals: basal release.
.
J Pharmacol Exp Ther. 316(1):208-15.
2005
OuYang W
,
Hemmings HC
. 2005.
Depression by isoflurane of the action potential and underlying voltage-gated ion currents in isolated rat neurohypophysial nerve terminals.
.
J Pharmacol Exp Ther. 312(2):801-8.
Hemmings HC
,
Akabas MH
,
Goldstein PA
,
Trudell JR
,
Orser BA
,
Harrison NL
. 2005.
Emerging molecular mechanisms of general anesthetic action.
.
Trends Pharmacol Sci. 26(10):503-10.
Hemmings HC
,
Yan W
,
Westphalen RI
,
Ryan TA
. 2005.
The general anesthetic isoflurane depresses synaptic vesicle exocytosis.
.
Mol Pharmacol. 67(5):1591-9.
Futter M
,
Uematsu K
,
Bullock SA
,
Kim Y
,
Hemmings HC
,
Nishi A
,
Greengard P
,
Nairn AC
. 2005.
Phosphorylation of spinophilin by ERK and cyclin-dependent PK 5 (Cdk5).
.
Proc Natl Acad Sci U S A. 102(9):3489-94.
Fu D
,
Vissavajjhala P
,
Hemmings HC
. 2005.
Volatile anaesthetic effects on phospholipid binding to synaptotagmin 1, a presynaptic Ca2+ sensor.
.
Br J Anaesth. 95(2):216-21.
2004
Hazlett EA
,
Buchsbaum MS
,
Kemether E
,
Bloom R
,
Platholi J
,
Brickman AM
,
Shihabuddin L
,
Tang C
,
Byne W
. 2004.
Abnormal glucose metabolism in the mediodorsal nucleus of the thalamus in schizophrenia.
.
Am J Psychiatry. 161(2):305-14.
Bálint E
,
Kitka T
,
Zachar G
,
Adám A
,
Hemmings HC
,
Csillag A
. 2004.
Abundance and location of DARPP-32 in striato-tegmental circuits of domestic chicks.
.
J Chem Neuroanat. 28(1-2):27-36.
Perouansky M
,
Hemmings HC
,
Pearce RA
. 2004.
Anesthetic effects on glutamatergic neurotransmission: lessons learned from a large synapse.
.
Anesthesiology. 100(3):470-2.
Ouyang W
,
Wang G
,
Hemmings HC
. 2004.
Distinct rat neurohypophysial nerve terminal populations identified by size, electrophysiological properties and neuropeptide content.
.
Brain Res. 1024(1-2):203-11.
Hemmings HC
. 2004.
Neuroprotection by Na+ channel blockade.
.
J Neurosurg Anesthesiol. 16(1):100-1.
Morrow PW
,
Tung HYLim
,
Hemmings HC
. 2004.
Rapamycin causes activation of protein phosphatase-2A1 and nuclear translocation of PCNA in CD4+ T cells.
.
Biochem Biophys Res Commun. 323(2):645-51.
Hazlett EA
,
Buchsbaum MS
,
Hsieh P
,
M Haznedar M
,
Platholi J
,
LiCalzi EM
,
Cartwright C
,
Hollander E
. 2004.
Regional glucose metabolism within cortical Brodmann areas in healthy individuals and autistic patients.
.
Neuropsychobiology. 49(3):115-25.
2003
Lingamaneni R
,
Hemmings HC
. 2003.
Differential interaction of anaesthetics and antiepileptic drugs with neuronal Na+ channels, Ca2+ channels, and GABA(A) receptors.
.
Br J Anaesth. 90(2):199-211.
Westphalen RI
,
Hemmings HC
. 2003.
Effects of isoflurane and propofol on glutamate and GABA transporters in isolated cortical nerve terminals.
.
Anesthesiology. 98(2):364-72.
OuYang W
,
Wang G
,
Hemmings HC
. 2003.
Isoflurane and propofol inhibit voltage-gated sodium channels in isolated rat neurohypophysial nerve terminals.
.
Mol Pharmacol. 64(2):373-81.
Kemether EM
,
Buchsbaum MS
,
Byne W
,
Hazlett EA
,
Haznedar M
,
Brickman AM
,
Platholi J
,
Bloom R
. 2003.
Magnetic resonance imaging of mediodorsal, pulvinar, and centromedian nuclei of the thalamus in patients with schizophrenia.
.
Arch Gen Psychiatry. 60(10):983-91.
Westphalen RI
,
Hemmings HC
. 2003.
Selective depression by general anesthetics of glutamate versus GABA release from isolated cortical nerve terminals.
.
J Pharmacol Exp Ther. 304(3):1188-96.
2002
New AS
,
Hazlett EA
,
Buchsbaum MS
,
Goodman M
,
Reynolds D
,
Mitropoulou V
,
Sprung L
,
Shaw RB
,
Koenigsberg H
,
Platholi J
et al.
. 2002.
Blunted prefrontal cortical 18fluorodeoxyglucose positron emission tomography response to meta-chlorophenylpiperazine in impulsive aggression.
.
Arch Gen Psychiatry. 59(7):621-9.
Pashkov VN
,
Hemmings HC
. 2002.
The effects of general anesthetics on norepinephrine release from isolated rat cortical nerve terminals.
.
Anesth Analg. 95(5):1274-81,tableofcontents.
Albert KA
,
Hemmings HC
,
Adamo AIB
,
Potkin SG
,
Akbarian S
,
Sandman CA
,
Cotman CW
,
Bunney WE
,
Greengard P
. 2002.
Evidence for decreased DARPP-32 in the prefrontal cortex of patients with schizophrenia.
.
Arch Gen Psychiatry. 59(8):705-12.
Shahani SK
,
Lingamaneni R
,
Hemmings HC
. 2002.
General anesthetic actions on norepinephrine, dopamine, and gamma-aminobutyric acid transporters in stably transfected cells.
.
Anesth Analg. 95(4):893-9,tableofcontents.
Pashkov VN
,
Westphalen RI
,
Hemmings HC
. 2002.
General anesthetics do not affect release of the neuropeptide cholecystokinin from isolated rat cortical nerve terminals.
.
Anesthesiology. 97(6):1500-6.
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